Benoît Roux Explained

Benoît Roux
Nationality:Canadian
Field:Biophysics
Work Institution:University of Montreal
Cornell University
University of Chicago
Alma Mater:University of Montreal
Harvard University[1]
Doctoral Advisor:Martin Karplus
Thesis Title:Theoretical Study of Ion Transport in the Gramicidin A Channel
Thesis Url:https://ui.adsabs.harvard.edu/abs/1990PhDT........69R/abstract
Thesis Year:1990
Prizes:Rutherford Memorial Medal
Fellow of the Biophysical Society of Canada
Fellow of the Royal Society of Canada
Website:http://thallium.bsd.uchicago.edu/

Benoît Roux is an Amgen Professor of Biochemistry and Molecular Biophysics at the University of Chicago. He has previously taught at University of Montreal and Weill Medical College of Cornell University. Benoît Roux was a recipient of the 1998 Rutherford Memorial Medal in Chemistry, awarded by the Royal Society of Canada.[2]

Life and career

Roux obtained B.Sc. and M.Sc. in physics from the University of Montreal in 1981 and 1984 respectively. He completed his Ph.D. at Harvard University under the supervision of Martin Karplus, graduating in 1990. He served at the French Alternative Energies and Atomic Energy Commission from 1991 to 1992 and was a Foreign Research Fellow at the Centre D’Etudes. He was a faculty member in the department of physics at the Université de Montréal until 1999, when he relocated to Weill Cornell Medicine. He relocated to the department of biochemistry and molecular biology at the University of Chicago in 2005. He also serves as a research scientist at the Center for Nanoscale Materials, a department of the Argonne National Laboratory.[3] He is an accomplished classical pianist, specializing in the work of Frédéric Chopin.

Research

His laboratory at the University of Chicago mostly uses theoretical techniques, such as classical molecular dynamics, to understand the functioning of biological systems at the molecular level. His research has investigated structure, dynamics, and the function of biological macromolecular systems such as ion channels, receptors, and protein kinases.[4]

He is a pioneer in the study of membrane proteins using molecular dynamics with explicit phospholipid molecules and solvent.[5] [6] His laboratory has also developed novel computational methods to improve efficiency and applicability of theoretical investigations to molecular recognition phenomena. His work has bridged theory and experiment in biophysics by employing ever-increasing computational power to further the understanding of the molecular basis of life.

Works

In 1996, he co-authored Biological Membranes: A Molecular Perspective from Computation and Experiment with Kenneth M. Merz.[7] In 2001, he co-edited a book with Oren M. Becker, Alexander D. MacKerell Jr., Benoit Roux, Masakatsu Watanabe, ``Computational Biochemistry and Biophysics. [8] In 2021, he authored a text on biophysical theory and simulations, Computational Modeling and Simulations of Biomolecular Systems.[9]

Honors, awards, and fellowships

External links

Notes and References

  1. Web site: Department of Biochemistry & Molecular Biology. dead . https://web.archive.org/web/20160124195845/http://bmb.uchospitals.edu/faculty/benoit-roux . 2016-01-24 .
  2. News: January 27, 2015. Faculty members receive named, distinguished service professorships. University of Chicago. May 11, 2019.
  3. Web site: Benoît Roux. University of Chicago. March 11, 2019.
  4. Web site: Benoît Roux. University of Chicago. May 11, 2019.
  5. Ion transport in a model gramicidin channel. Structure and thermodynamics. B. Roux and M. Karplus Biophys. J. 1991;59(5):961-981.
  6. Theoretical and computational models of ion channels. B. Roux Curr Opin Struct Biol. 2002;12(2):182-189.
  7. Book: Merz, Kenneth M.. Roux, Benoît. Biological Membranes: A Molecular Perspective from Computation and Experiment. 1996. Birkhäuser. 10.1007/978-1-4684-8580-6. 1468485806. 30908633.
  8. Book: ROUX, BENOIT. Computational Biochemistry and Biophysics.. 2001. Taylor Francis.
  9. Book: ROUX, BENOIT. COMPUTATIONAL MODELING AND SIMULATIONS OF BIOMOLECULAR SYSTEMS : simulations of... biomolecular systems.. 2021. WORLD SCIENTIFIC PUB. 978-981-12-3275-6. [S.l.]. 1225976875.
  10. Special Issue: Membrane Protein Simulations and Free Energy Approaches: In honor of Professor Benoit Roux's 60th birthday . Journal of Computational Chemistry . February 15, 2020 . 41 . 5 . C1, 379-481 . 30 June 2020.
  11. Web site: Past Award Winners. 21 October 2018 . Royal Society of Canada. May 11, 2019.
  12. Web site: 2017 Fellow of the BSC: Dr. Benoît Roux. Christoff, Craig. Biophysical Society of Canada. April 19, 2017. May 11, 2019.
  13. Web site: Wood. Matt. 2021-09-08. Benoit Roux, PhD, elected to the Royal Society of Canada. 2021-09-13. Science Life Biological Sciences Division Research News. en-US.
  14. Web site: 2024-04-18. Two UChicago scholars elected as 2023 American Association for the Advancement of Science fellows. 2024-04-18. news.uchicago.edu. en-US.