Bencyclane Explained

Bencyclane is an antispasmodic, vasodilator, and platelet aggregation inhibitor.[1]

Synthesis

Grignard addition of benzylmagnesiumbromide to suberone would give 1-benzylcycloheptanol [4006-73-9] (1'). Williamson ether synthesis with 3-dimethylaminopropylchloride [109-54-6] (2) completed the synthesis of bencyclane (3).

See also

Notes and References

  1. Book: The Dictionary of Drugs: Chemical Data, Structures and Bibliographies . J. Elks . Springer . 2014 .