Ben G. Davis Explained

Ben Davis
Birth Name:Benjamin Guy Davis
Birth Date:1970 8, df=yes[1] [2]
Birth Place:Hatfield, Hertfordshire
Other Names:Benjamin
Education:Nottingham High School
Alma Mater:University of Oxford (BA, DPhil)
Thesis Title:Synthesis of inhibitors of sugar processing enzymes
Thesis Url:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.711593
Thesis Year:1996
Doctoral Advisor:George Fleet[3]
Academic Advisors:J. Bryan Jones[4]

Benjamin Guy Davis [5] [6] (born 8 August 1970) is Professor of Chemical biology[7] [8] in the Department of Pharmacology and a member of the Faculty (by courtesy) in the Department of Chemistry at the University of Oxford[9] [10] and a Fellow of Pembroke College, Oxford.[11] He holds the role of Science Director for Next Generation Chemistry[12] (2019-2024) and Deputy Director (2020-) at the Rosalind Franklin Institute.

Education

Davis was privately educated at Nottingham High School followed by the University of Oxford where he was awarded Bachelor of Arts degree in Chemistry (with Chemical Pharmacology) in 1993 and a Doctor of Philosophy in 1996 supervised by .[13] [14] He was a student of Keble College, Oxford.[3]

Research and career

After his PhD, Davis spent two years as a postdoctoral research fellow in the laboratory of [15] at the University of Toronto, exploring protein chemistry and biocatalysis.[5] There he developed, with Jones and Genencor International Inc., early examples of targeted protein degradation systems.[16] In 1998 he returned to the United Kingdom to take up a lectureship at Durham University. In the autumn of 2001 he moved to the Dyson Perrins Laboratory in the Department of Chemistry and received a fellowship at Pembroke College, Oxford.[17] He was promoted to Professor of Chemistry in 2005.[5] In 2021 in a new partnership between the Rosalind Franklin Institute and the University of Oxford he took up a joint position between Medical Sciences in the Department of Pharmacology and the role of Science Director for Next Generation Chemistry; this post lasts until 2024. From November 2023 to April 2024 he was the Interim Director of the Institute.

His group's research centres on the chemical understanding and exploitation of biomolecular function (Synthetic Biology, Chemical Biology and Chemical Medicine), with an emphasis on carbohydrates and proteins. In particular, the group's interests encompass synthesis and methodology; target biomolecule synthesis; inhibitor/probe/substrate design; biocatalysis; enzyme and biomolecule mechanism; biosynthetic pathway determination; protein engineering; drug delivery; molecular biology; structural biology; cell biology; glycobiology; molecular imaging and in vivo biology.[5]

Research in the Davis laboratory has been funded by the Engineering and Physical Sciences Research Council, the Biotechnology and Biological Sciences Research Council, the Medical Research Council, UCB-Celltech, AstraZeneca, the European Union, GlaxoSmithKline, Cancer Research UK, the Wellcome Trust and the Royal Society.[3] He has supervised numerous postdoctoral researchers and doctoral students to completion.[18]

Awards and honours

Davis was elected a Fellow of the Royal Society in 2015.[5] His certificate of election reads:

In 2017, he was elected a Member of the Academia Europea[19] and in 2019, he was elected a Fellow of the Academy of Medical Sciences.[20]

He was also a recipient of the Mullard Award from the Royal Society in 2005, the Philip Leverhulme Prize in 2002 and the Meldola Medal and Prize in 1999 from the Royal Society of Chemistry.[21] He won the Whistler Award[22] of the International Carbohydrate Organization in 2016. He also received the Davy Medal ("awarded for outstanding contributions in the field of chemistry"[23]) from the Royal Society in 2020.

Notes and References

  1. Anon . 10.1002/anie.200901068 . Author profile: Benjamin G. Davis . . 48 . 22 . 3900 . 2009.
  2. 10.1002/chemv.201000012 . Future Visions of Chemistry: Ben Davis . . 2010 . Davis . B. .
  3. Web site: https://web.archive.org/web/20130615185952/http://users.ox.ac.uk/~dplb0149/people/bdavis.html. 15 June 2013. The Davis Group. University of Oxford.
  4. 15858635. 2005. Ambrosi. M. Lectins: Tools for the molecular understanding of the glycocode. Organic and Biomolecular Chemistry. 3. 9. 1593–608. Cameron. N. R.. Davis. B. G.. 10.1039/b414350g.
  5. Web site: Professor Benjamin Davis FRS . . London . Anon. 2015. https://web.archive.org/web/20151117101055/https://royalsociety.org/people/benjamin-davis-11314/ . 17 November 2015 . One or more of the preceding sentences incorporates text from the royalsociety.org website where:
  6. Web site: Professor Benjamin Davis FRS . 2 May 2015 . https://web.archive.org/web/20150502131121/https://royalsociety.org/people/fellowship/2015/benjamin-davis/ . London. The Royal Society.
  7. Web site: Rosalind Franklin Institute and Pharmacology announce strategic partnership in Next Generation Chemistry — Department of Pharmacology . 2022-11-24 . www.pharm.ox.ac.uk.
  8. Web site: 2021-12-07 . Franklin and Oxford Pharmacology join forces . 2022-11-24 . Harwell Campus . en-GB.
  9. Web site: https://web.archive.org/web/20080602083757/http://www.rsc.org/Publishing/Journals/cb/Volume/2007/2/InterviewwithBenDavis.asp. 2 June 2008. Interview with Ben Davis: Sugar Solutions. Royal Society of Chemistry. Anon. 2007.
  10. Web site: The Davis Group - Home. Philippe. Garnier. Users.ox.ac.uk.
  11. Web site: Professor Ben Davis - Pembroke College. Pmb.ox.ac.uk. 21 May 2018. 14 April 2018. https://web.archive.org/web/20180414060245/https://www.pmb.ox.ac.uk/fellows-staff/profiles/professor-ben-davis. dead.
  12. Web site: Science Director, Next Generation Chemistry - Professor Ben Davis . 2022-11-24 . Rosalind Franklin Institute . en-GB.
  13. Web site: George Fleet . 2023-11-18 . www.chem.ox.ac.uk . en.
  14. DPhil . Benjamin Guy. Davis . Synthesis of inhibitors of sugar processing enzymes . University of Oxford . 1996 . . jisc.ac.uk. 1064614676.
  15. Web site: Profile of J. Bryan Jones . 2023-11-18 . sites.chem.utoronto.ca.
  16. WO2000064485A2. Specifically targeted catalytic antagonists and uses thereof. 2000-11-02. Davis. Jones. Bott. Sanford. Benjamin G.. John Bryan. Richard R.. Karl John.
  17. Barlow . John . 2003 . Welcoming New Fellows, Ben Davis . Pembroke College Record . 2000-2003 . 19 . Pembroke College, Oxford.
  18. Web site: The Davis Group - Former Members . 2023-11-18 . users.ox.ac.uk.
  19. Web site: Academy of Europe: Davis Benjamin . 2022-11-24 . www.ae-info.org.
  20. Web site: 8 May 2019 . New Fellows: 50 top biomedical and health scientists join the Academy . 13 June 2019 . Academy of Medical Sciences, United Kingdom.
  21. Web site: The Davis Group - Ben G. Davis. Philippe. Garnier. Users.ox.ac.uk. 21 May 2018.
  22. Web site: Roy L Whistler International Award in Carbohydrate Chemistry – International Carbohydrate Organisation . 2022-11-24 . en-US.
  23. Web site: Davy Medal Royal Society . 2022-11-24 . royalsociety.org.