Bay R 1531 Explained

Bay R 1531 is a tricyclic tryptamine derivative which acts as a selective serotonin receptor 5-HT1A agonist. It was researched unsuccessfully for the treatment of stroke but remains in use for scientific research.[1] [2] [3] [4]

See also

Notes and References

  1. Bielenberg GW, Burkhardt M . 5-hydroxytryptamine1A agonists. A new therapeutic principle for stroke treatment . Stroke . 21 . 12 Suppl . IV161-3 . December 1990 . 2148035 .
  2. Critchley MA, Njung'e K, Handley SL . Actions and some interactions of 5-HT1A ligands in the elevated X-maze and effects of dorsal raphe lesions . Psychopharmacology . 106 . 4 . 484–90 . 1992 . 1533721 . 10.1007/bf02244819 . 8404850 .
  3. Canto de Souza A, Nunes de Souza RL, Péla IR, Graeff FG . High intensity social conflict in the Swiss albino mouse induces analgesia modulated by 5-HT1A receptors . Pharmacology, Biochemistry, and Behavior . 56 . 3 . 481–6 . March 1997 . 9077586 . 10.1016/s0091-3057(96)00246-8 . 20078255 .
  4. Canto-de-Souza A, Nunes de Souza RL, Pelá IR, Graeff FG . Involvement of the midbrain periaqueductal gray 5-HT1A receptors in social conflict induced analgesia in mice . European Journal of Pharmacology . 345 . 3 . 253–6 . March 1998 . 9592023 . 10.1016/s0014-2999(98)00018-1 .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Bay R 1531".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.