| Conflict: | Battle of Santomé |
| Partof: | the Dominican War of Independence |
| Date: | 22 December 1855; 168 years ago |
| Place: | Savannah of Santomé, San Juan Province |
| Result: | Dominican victory |
| Combatant1: |  Dominican Republic |
| Commander1: | José María Cabral |
| Commander2: | Antoine Pierrot |
| Strength1: | 4,500 |
| Strength2: | 12,000 |
| Casualties1: | moderate |
| Casualties2: | 695 killed, many wounded |
The Battle of Santomé (Spanish; Castilian: Batalla de Santomé) was a major battle during the years after the Dominican War of Independence and was fought on 22 December 1855, in the province of San Juan. A detachment of Dominican troops forming part of the Army of the South, led by General José María Cabral, defeated an outnumbering force of the Haitian Army led by Antoine Pierrot. Almost 700 Haitian soldiers perished in the battle, and the rest, many of them wounded, were forced to retreat, being pushed back as far as the Fortress of Cachimán and subsequently beyond the border. The Haitians met defeat on the same day at the Battle of Cambronal.