| Conflict: | Battle of Santa Ana |
| Partof: | the Portuguese conquest of the Banda Oriental |
| Date: | 1816 |
| Place: | Rio Grande do Sul, Brazil |
| Result: | Federal League victory |
| Combatant1: | United Kingdom of Portugal, Brazil and the Algarves |
| Combatant2: | Federal League |
| Commander1: | Alexandre Queirós |
| Commander2: | General Sotelo |
| Strength1: | Unknown |
| Strength2: | Unknown |
| Casualties1: | 60 men killed |
| Casualties2: | Unknown |
The Battle of Santa Ana took place between the Luso-Brazilian forces under the command of Alexandre Queirós in Rio Grande do Sul, modern-day Brazil.After the Luso-Brazilian attack, oriental leader José Gervasio Artigas attempted to take the battle to the invading forces by invading Brazil. The battle lasted for 3 hours and ended with a Luso-Brazilian defeat.