| Conflict: | Battle of Mstislavl |
| Partof: | the Muscovite–Lithuanian Wars |
| Date: | 4 November 1501 |
| Place: | Near Mstislavl, Mogilev Region |
| Coordinates: | 54°N 74°W |
| Result: | Russian victory |
| Combatant1: | Grand Duchy of Lithuania |
| Combatant2: | Grand Duchy of Moscow Principality of Novgorod-Seversk |
| Commander1: | Princes Mstislavsky Ostap Dashkevych |
| Casualties1: | About 7,000 |
| Casualties2: | Unknown |
The Battle of Mstislavl took place on 4 November 1501 between the forces of the Grand Duchy of Lithuania and the forces of the Grand Duchy of Moscow and Principality of Novgorod-Seversk. The Lithuanian forces were defeated.
The Muscovite–Lithuanian Wars renewed in 1500. In 1501, Ivan III of Russia sent a new force under the command of towards Mstislavl. Local princes Mstislavsky together with Ostap Dashkevych organized the defense and were badly beaten on 4 November. They retreated to Mstislavl and Mozhayskiy decided not to attack the castle. Instead, Russian forces besieged the city and pillaged surrounding areas.
Lithuanians organized a relief force, brought by Great Hetman Stanislovas Kęsgaila. Neither Mozhayskiy nor Kęsgaila dared to attack and the Russian forces retreated without a battle.