Barx homeobox 1 explained
BARX homeobox 1 is a protein that in humans is encoded by the BARX1 gene.[1]
Function
This gene encodes a member of the Bar subclass of homeobox transcription factors. Studies of the mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. [provided by RefSeq, Jul 2008].
Further reading
- Lowry RB, Gould DB, Walter MA, Savage PR . Absence of PITX2, BARX1, and FOXC1 mutations in De Hauwere syndrome (Axenfeld-Rieger anomaly, hydrocephaly, hearing loss): a 25-year follow up . Am. J. Med. Genet. A . 143A . 11 . 1227–30 . June 2007 . 17486624 . 10.1002/ajmg.a.31732 . 44935786 .
- Krivicka-Uzkurele B, Pilmane M, Akota I . Barx1, growth factors and apoptosis in facial tissue of children with clefts . Stomatologija . 10 . 2 . 62–6 . 2008 . 18708738 .
- Vieira AR, McHenry TG, Daack-Hirsch S, Murray JC, Marazita ML . Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts . Genet. Med. . 10 . 9 . 668–74 . September 2008 . 18978678 . 2734954 . 10.1097/GIM.0b013e3181833793 .
- Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Nguyen TT, Christiansen L, Lidral AC, Murray JC . Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia . PLOS ONE . 5 . 7 . e11493 . July 2010 . 20634891 . 2901336 . 10.1371/journal.pone.0011493 . 2010PLoSO...511493J . free .
Notes and References
- Web site: Entrez Gene: BARX homeobox 1. 2018-07-10.
