Baek Sung-hee explained
Baek Sung-hee (born 1970) is a South Korean scientist specialising in molecular genetics. Her work is focused on the chromatin dynamics and epigenetic regulatory mechanism in cancer. She received her BS, MS, and Ph.D. degrees from Seoul National University. Following her postdoctoral research in Michael Rosenfeld’s lab at HHMI and following research assistant professor at HHMI, she joined the faculty of Seoul National University in 2003, and now works as an associate professor. Baek received numerous awards and honors, including the L’Oreal-UNESCO for Women in Science Award.
Awards
Publications
- 10.1016/j.molcel.2012.09.004 . EZH2 Generates a Methyl Degron that is Recognized by the DCAF1/DDB1/CUL4 E3 Ubiquitin Ligase Complex . 2012 . Lee . Ji Min . Lee . Jason S. . Kim . Hyunkyung . Kim . Kyeongkyu . Park . Hyejin . Kim . Ji-Young . Lee . Seung Hoon . Kim . Ik Soo . Kim . Joomyung . Molecular Cell . 48 . 4 . 572–86 . 23063525 . Lee . Minkyoung . Chung . Chin Ha . Seo . Sang-Beom . Yoon . Jong-Bok . Ko . Eunyoung . Noh . Dong-Young . Kim . Keun Il . Kim . Kyeong Kyu . Baek . Sung Hee. free .
- 10.1016/j.molcel.2012.03.021 . Roles of Mis18α in Epigenetic Regulation of Centromeric Chromatin and CENP-A Loading . 2012 . Kim . Ik Soo . Lee . Minkyoung . Park . Koog Chan . Jeon . Yoon . Park . Joo Hyeon . Hwang . Eun Ju . Jeon . Tae Im . Ko . Seoyoung . Lee . Ho . Molecular Cell . 46 . 3 . 260–73 . 22516971 . Baek . Sung Hee . Kim . Keun Il. free .
- 10.1016/j.molcel.2011.09.023 . DNA Damage-Induced RORα is Crucial for p53 Stabilization and Increased Apoptosis . 2011 . Kim . Hyunkyung . Lee . Ji Min . Lee . Gina . Bhin . Jinhyuk . Oh . Se Kyu . Kim . Kyeongkyu . Pyo . Ki Eun . Lee . Jason S. . Yim . Hwa Young . Molecular Cell . 44 . 5 . 797–810 . 22152482 . Kim . Keun Il . Hwang . Daehee . Chung . Jongkyeong . Baek . Sung Hee. free .
- 2011PNAS..10813510L . Hypoxia-induced methylation of a pontin chromatin remodeling factor . Lee . Jason S. . Kim . Yunho . Bhin . Jinhyuk . Shin . Hi-Jai R. . Nam . Hye Jin . Lee . Seung Hoon . Yoon . Jong-Bok . Binda . Olivier . Gozani . Or . 108 . 2011 . 13510–5 . Proceedings of the National Academy of Sciences . 10.1073/pnas.1106106108 . 33 . 21825155 . 3158161 . Hwang . D. . Baek . S. H.. free .
- 10.1016/j.molcel.2011.03.022 . When Signaling Kinases Meet Histones and Histone Modifiers in the Nucleus . 2011 . Baek . Sung Hee . Molecular Cell . 42 . 3 . 274–84 . 21549306. free .
- 10.1016/j.molcel.2010.06.008 . Negative Regulation of Hypoxic Responses via Induced Reptin Methylation . 2010 . Lee . Jason S. . Kim . Yunho . Kim . Ik Soo . Kim . Bogyou . Choi . Hee June . Lee . Ji Min . Shin . Hi-Jai R. . Kim . Jung Hwa . Kim . Ji-Young . Molecular Cell . 39 . 71–85 . 20603076 . 1 . Seo . Sang-Beom . Lee . Ho . Binda . Olivier . Gozani . Or . Semenza . Gregg L. . Kim . Minhyung . Kim . Keun Il . Hwang . Daehee . Baek . Sung Hee . 4651011.
- 10.1016/j.molcel.2009.12.022 . RORα Attenuates Wnt/β-Catenin Signaling by PKCα-Dependent Phosphorylation in Colon Cancer . 2010 . Lee . Ji Min . Kim . Ik Soo . Kim . Hyunkyung . Lee . Jason S. . Kim . Kyeongkyu . Yim . Hwa Young . Jeong . Jiyeong . Kim . Jung Hwa . Kim . Ji-Young . Molecular Cell . 37 . 2 . 183–95 . 20122401 . Lee . Hanna . Seo . Sang-Beom . Kim . Hogeun . Rosenfeld . Michael G. . Kim . Keun Il . Baek . Sung Hee. free .
- 10.1016/j.devcel.2008.03.018 . When ATPases Pontin and Reptin Met Telomerase . 2008 . Baek . Sung Hee . Developmental Cell . 14 . 4 . 459–61 . 18410720. free .
- 2007PNAS..10420793K . 25450980 . SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells . Kim . Jung Hwa . Lee . Ji Min . Nam . Hee June . Choi . Jung Woo . Yang . Jung Woo . Lee . Jason S. . Kim . Mi Hyang . Kim . Su-Il . Chung . Chin Ha . 104 . 2007 . 20793–8 . Proceedings of the National Academy of Sciences . 10.1073/pnas.0710343105 . 52 . 18087039 . 2410081 . Kim . K. I. . Baek . S. H.. free .
- 10.1038/ncb1415 . Roles of sumoylation of a reptin chromatin-remodelling complex in cancer metastasis . 2006 . Kim . Jung Hwa . Choi . Hee June . Kim . Bogyou . Kim . Mi Hyang . Lee . Ji Min . Kim . Ik Soo . Lee . Moon Hee . Choi . Soo Joon . Kim . Keun Il . Nature Cell Biology . 8 . 6 . 631–9 . 16699503 . Kim . Su-Il . Chung . Chin Ha . Baek . Sung Hee. 36037879 .
- 10.1016/j.cell.2005.12.032 . Macrophage/Cancer Cell Interactions Mediate Hormone Resistance by a Nuclear Receptor Derepression Pathway . 2006 . Zhu . Ping . Baek . Sung Hee . Bourk . Eliot M. . Ohgi . Kenneth A. . Garcia-Bassets . Ivan . Sanjo . Hideki . Akira . Shizuo . Kotol . Paul F. . Glass . Christopher K. . Cell . 124 . 3 . 615–29 . 16469706 . Rosenfeld . Michael G. . Rose . David W.. free .
- 2006PNAS..103.3100B . 30048543 . Ligand-specific allosteric regulation of coactivator functions of androgen receptor in prostate cancer cells . Baek . Sung Hee . Ohgi . Kenneth A. . Nelson . Charles A. . Welsbie . Derek . Chen . Charlie . Sawyers . Charles L. . Rose . David W. . Rosenfeld . Michael G. . 103 . 2006 . 3100–5 . Proceedings of the National Academy of Sciences . 10.1073/pnas.0510842103 . 9 . 16492776 . 1413901. free .
- 10.1038/nature03452 . Transcriptional regulation of a metastasis suppressor gene by Tip60 and β-catenin complexes . 2005 . Kim . Jung Hwa . Kim . Bogyou . Cai . Ling . Choi . Hee June . Ohgi . Kenneth A. . Tran . Chris . Chen . Charlie . Chung . Chin Ha . Huber . Otmar . Nature . 434 . 7035 . 921–6 . 15829968. 2005Natur.434..921K . Rose . David W. . Sawyers . Charles L. . Rosenfeld . Michael G. . Baek . Sung Hee . 4418988 .
- Chrissa . Kioussi . Paola . Briata . Sung Hee . Baek . David W. . Rose . Natasha S. . Hamblet . Thomas . Herman . Kenneth A. . Ohgi . Chijen . Lin . Anatoli . Gleiberman . Identification of a Wnt/Dvl/β-Catenin → Pitx2 Pathway Mediating Cell-Type-Specific Proliferation during Development . 12464179 . 2002 . 111 . 5 . 673–85 . Cell . 10.1016/S0092-8674(02)01084-X . Wang . Jianbo . Brault . V . Ruiz-Lozano . P . Nguyen . HD . Kemler . R . Glass . CK . Wynshaw-Boris . A . Rosenfeld . MG. free .
- Sung Hee . Baek . Kenneth A. . Ohgi . David W. . Rose . Edward H. . Koo . Christopher K. . Glass . Michael G. . Rosenfeld . Exchange of N-CoR Corepressor and Tip60 Coactivator Complexes Links Gene Expression by NF-κB and β-Amyloid Precursor Protein . 12150997 . 2002 . 110 . 1 . 55–67 . Cell . 10.1016/S0092-8674(02)00809-7. free .
External links
Notes and References
- Web site: 유네스코 소식 - 유네스코한국위원회 . Unesco.or.kr . 2005-06-22 . 2013-11-29 . dead . https://web.archive.org/web/20131203020012/http://www.unesco.or.kr/news_center/sub_01_view.asp?articleid=676&cate=A . 2013-12-03 .
- Web site: THE SCIENCE : 백성희·이레나·원미숙 씨, 올해의 여성과학기술자상 수상 . News.dongascience.com . 2013-11-29.