Bacteroidales-1 RNA motif explained

Bacteroidales-1 RNA
Width:250
Symbol:Bacteroidales-1
Rfam:RF01693
Rna Type:sRNA
Tax Domain:Bacteroidales

The Bacteroidales-1 RNA motif is a conserved RNA structure identified by bioinformatics.[1] It has been identified only in bacteria within the order (biology) Bacteroidales. Its presumed length is marked by a promoter on one end that conforms to an alternate consensus sequence that is common in the phylum Bacteroidota, and its 3′ end is indicated by predicted transcription terminators.[2] It is often located downstream of a gene that encodes the L20 ribosomal subunit, although it is unclear whether there is a functional reason underlying this apparent association.

Bacteroidales-1 RNA motif has been reported as a 6S RNA homologue by a report of Bacteroides thetaiotaomicron transcriptome map.[3] The existence of small product RNAs (pRNAs) that rescue sequestered RNA polymerases, validated 6S RNA-mediated regulation of transcriptional activity.

See also

Notes and References

  1. Weinberg Z, Wang JX, Bogue J . Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea and their metagenomes . Genome Biol . 11 . 3 . R31 . March 2010 . 20230605 . 10.1186/gb-2010-11-3-r31 . 2864571. etal . free .
  2. Bayley DP, Rocha ER, Smith CJ . Analysis of cepA and other Bacteroides fragilis genes reveals a unique promoter structure . FEMS Microbiol. Lett. . 193 . 1 . 149–154 . December 2000 . 11094294 . 10.1111/j.1574-6968.2000.tb09417.x. free .
  3. Ryan. Daniel. Jenniches. Laura. Reichardt. Sarah. Barquist. Lars. Westermann. Alexander J.. 2020-07-16. A high-resolution transcriptome map identifies small RNA regulation of metabolism in the gut microbe Bacteroides thetaiotaomicron. Nature Communications. en. 11. 1. 3557. 10.1038/s41467-020-17348-5. 32678091 . 2041-1723. 7366714.