Bacterial neuraminidase explained

Symbol:BNR
BNR/Asp-box repeat
Pfam:PF02012
Pfam Clan:CL0434
Interpro:IPR002860
Scop:1euu
Pdb:,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,

Bacterial neuraminidase is type of neuraminidase and a virulence factor for many bacteria including Bacteroides fragilis and Pseudomonas aeruginosa.Its function is to cleave a sialic acid residue off ganglioside-GM1 (a modulator of cell surface and receptor activity) turning it into asialo-GM1 to which type 4 pili (attachment factors) bind preferentially.