Bacillus-plasmid RNA motif explained

Bacillus-plasmid RNA
Symbol:Bacillus-plasmid
Rfam:RF01691
Tax Domain:Bacillus, Lactobacillus

The Bacillus-plasmid RNA motif is a predicted conserved RNA structure usually located in plasmids.[1] It is known in species under the genera Bacillus and Lactobacillus. In Bacillus subtilis, it is found upstream of the hypothetical gene ydcS, whose function is unknown.

The fact that the RNA structure is typically found in plasmids suggests that it might be involved in the regulation plasmid copy number by a cis-antisense mechanism in a manner similar to that of R1162-like plasmid antisense RNA.[2] However, the Bacillus-plasmid RNA motif does not appear to be homologous to any such known RNA.

Notes and References

  1. Weinberg Z, Wang JX, Bogue J . Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea, and their metagenomes . Genome Biol . 11 . 3 . R31 . March 2010 . 20230605 . 2864571 . 10.1186/gb-2010-11-3-r31 . etal . free .
  2. Kim K, Meyer RJ . Copy-number of broad host-range plasmid R1162 is regulated by a small RNA . Nucleic Acids Res. . 14 . 20 . 8027–8046 . October 1986 . 2430262 . 311832 . 10.1093/nar/14.20.8027.