BZW1 explained

Basic leucine zipper and W2 domain-containing protein 1 is a protein that in humans is encoded by the BZW1 gene and expressed in the nucleus.[1] [2] [3] It enables RNA and cadherin binding activity.[4]

Salivary gland carcinoma and eastern equine encephalitis are associated with BZW1.

Interactions

BZW1 has been shown to interact with PSTPIP1[5] and CDC5L.[6]

Further reading

Notes and References

  1. Machado RD, Pauciulo MW, Fretwell N, Veal C, Thomson JR, Vilariño Güell C, Aldred M, Brannon CA, Trembath RC, Nichols WC . A physical and transcript map based upon refinement of the critical interval for PPH1, a gene for familial primary pulmonary hypertension. The International PPH Consortium . Genomics . 68 . 2 . 220–8 . September 2000 . 10964520 . 10.1006/geno.2000.6291 .
  2. Mitra P, Vaughan PS, Stein JL, Stein GS, van Wijnen AJ . Purification and functional analysis of a novel leucine-zipper/nucleotide-fold protein, BZAP45, stimulating cell cycle regulated histone H4 gene transcription . Biochemistry . 40 . 35 . 10693–9 . August 2001 . 11524015 . 10.1021/bi010529o .
  3. Web site: Entrez Gene: BZW1 basic leucine zipper and W2 domains 1.
  4. Web site: BZW1 basic leucine zipper and W2 domains 1 [Homo sapiens (human)] - Gene - NCBI ]. 2023-10-20 . www.ncbi.nlm.nih.gov.
  5. Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D . Large-scale mapping of human protein-protein interactions by mass spectrometry . Mol. Syst. Biol. . 3 . 1 . 89 . 2007 . 17353931 . 1847948 . 10.1038/msb4100134 .
  6. Ajuh P, Kuster B, Panov K, Zomerdijk JC, Mann M, Lamond AI . Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry . EMBO J. . 19 . 23 . 6569–81 . December 2000 . 11101529 . 305846 . 10.1093/emboj/19.23.6569 .