BRSK2 explained
BR serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the BRSK2 gene.[1] [2] [3]
Further reading
- Stanchi F, Bertocco E, Toppo S, Dioguardi R, Simionati B, Cannata N, Zimbello R, Lanfranchi G, Valle G . Characterization of 16 novel human genes showing high similarity to yeast sequences . Yeast . 18 . 1 . 69–80 . Jan 2001 . 11124703 . 10.1002/1097-0061(200101)18:1<69::AID-YEA647>3.0.CO;2-H . 21397515 . free .
- Lizcano JM, Göransson O, Toth R, Deak M, Morrice NA, Boudeau J, Hawley SA, Udd L, Mäkelä TP, Hardie DG, Alessi DR . LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1 . The EMBO Journal . 23 . 4 . 833–43 . Feb 2004 . 14976552 . 381014 . 10.1038/sj.emboj.7600110 .
- Lu R, Niida H, Nakanishi M . Human SAD1 kinase is involved in UV-induced DNA damage checkpoint function . The Journal of Biological Chemistry . 279 . 30 . 31164–70 . Jul 2004 . 15150265 . 10.1074/jbc.M404728200 . free .
- Sabater L, Gómez-Choco M, Saiz A, Graus F . BR serine/threonine kinase 2: a new autoantigen in paraneoplastic limbic encephalitis . Journal of Neuroimmunology . 170 . 1–2 . 186–90 . Dec 2005 . 16165222 . 10.1016/j.jneuroim.2005.08.011 . 2531035 .
- Inoue E, Mochida S, Takagi H, Higa S, Deguchi-Tawarada M, Takao-Rikitsu E, Inoue M, Yao I, Takeuchi K, Kitajima I, Setou M, Ohtsuka T, Takai Y . SAD: a presynaptic kinase associated with synaptic vesicles and the active zone cytomatrix that regulates neurotransmitter release . Neuron . 50 . 2 . 261–75 . Apr 2006 . 16630837 . 10.1016/j.neuron.2006.03.018 . 15232412 . free .
- Guo Z, Tang W, Yuan J, Chen X, Wan B, Gu X, Luo K, Wang Y, Yu L . BRSK2 is activated by cyclic AMP-dependent protein kinase A through phosphorylation at Thr260 . Biochemical and Biophysical Research Communications . 347 . 4 . 867–71 . Sep 2006 . 16870137 . 10.1016/j.bbrc.2006.06.178 .
Notes and References
- Miura K, Masuzaki H, Ishimaru T, Niikawa N, Jinno Y . A HhaI/BstUI polymorphism in a novel gene at human chromosome 11p15.5 . Journal of Human Genetics . 43 . 4 . 283–4 . Jan 1999 . 9852686 . 10.1007/s100380050092 . free .
- Miura K, Miyoshi O, Yun K, Inazawa J, Miyamoto T, Hayashi H, Masuzaki H, Yoshimura S, Niikawa N, Jinno Y, Ishimaru T . Repeat-directed isolation of a novel gene preferentially expressed from the maternal allele in human placenta . Journal of Human Genetics . 44 . 1 . 1–9 . Mar 1999 . 9929968 . 10.1007/s100380050096 . free .
- Web site: Entrez Gene: BRSK2 BR serine/threonine kinase 2.