BRL-44408 explained

BRL-44408 is a drug used in scientific research which acts as a selective antagonist for the α2A adrenoreceptor.[1] It has been suggested as having potential therapeutic application in the treatment of extrapyramidal side effects produced by some antipsychotic medications.[2]

Notes and References

  1. Alberts P . Subtype classification of presynaptic alpha 2-adrenoceptors . General Pharmacology . 24 . 1 . 1–8 . January 1993 . 8387042 . 10.1016/0306-3623(93)90003-g.
  2. Imaki J, Mae Y, Shimizu S, Ohno Y . Therapeutic potential of alpha2 adrenoceptor antagonism for antipsychotic-induced extrapyramidal motor disorders . Neuroscience Letters . 454 . 2 . 143–7 . April 2009 . 19429072 . 10.1016/j.neulet.2009.03.001 . 38109591 .

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