BRK1 explained

BRICK1 is a putative micropeptide protein that in humans is encoded by the C3orf10 gene.^{[1] [2]}

Further reading

• Cascón A, Escobar B, Montero-Conde C, Rodríguez-Antona C, Ruiz-Llorente S, Osorio A, Mercadillo F, Letón R, Campos JM, García-Sagredo JM, Benítez J, Malumbres M, Robledo M . Loss of the actin regulator HSPC300 results in clear cell renal cell carcinoma protection in Von Hippel-Lindau patients . Human Mutation . 28 . 6 . 613–21 . Jun 2007 . 17311301 . 10.1002/humu.20496 . 20428491 .
• Mayne M, Moffatt T, Kong H, McLaren PJ, Fowke KR, Becker KG, Namaka M, Schenck A, Bardoni B, Bernstein CN, Melanson M . CYFIP2 is highly abundant in CD4+ cells from multiple sclerosis patients and is involved in T cell adhesion . European Journal of Immunology . 34 . 4 . 1217–27 . Apr 2004 . 15048733 . 10.1002/eji.200324726 . free .
• Eden S, Rohatgi R, Podtelejnikov AV, Mann M, Kirschner MW . Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck . Nature . 418 . 6899 . 790–3 . Aug 2002 . 12181570 . 10.1038/nature00859 . 2002Natur.418..790E . 4350733 .
• Witke W, Podtelejnikov AV, Di Nardo A, Sutherland JD, Gurniak CB, Dotti C, Mann M . In mouse brain profilin I and profilin II associate with regulators of the endocytic pathway and actin assembly . The EMBO Journal . 17 . 4 . 967–76 . Feb 1998 . 9463375 . 1170446 . 10.1093/emboj/17.4.967 .
• Kitamura T, Kitamura Y, Yonezawa K, Totty NF, Gout I, Hara K, Waterfield MD, Sakaue M, Ogawa W, Kasuga M . Molecular cloning of p125Nap1, a protein that associates with an SH3 domain of Nck . Biochemical and Biophysical Research Communications . 219 . 2 . 509–14 . Feb 1996 . 8605018 . 10.1006/bbrc.1996.0264 . 20.500.14094/D1001555 . free .

External links

• • PDBe-KB provides an overview of all the structure information available in the PDB for Human Protein BRICK1

Notes and References

1. Maranchie JK, Afonso A, Albert PS, Kalyandrug S, Phillips JL, Zhou S, Peterson J, Ghadimi BM, Hurley K, Riss J, Vasselli JR, Ried T, Zbar B, Choyke P, Walther MM, Klausner RD, Linehan WM . Solid renal tumor severity in von Hippel Lindau disease is related to germline deletion length and location . Human Mutation . 23 . 1 . 40–6 . Jan 2004 . 14695531 . 10.1002/humu.10302 . 20671312 . free .
2. Web site: Entrez Gene: C3orf10 chromosome 3 open reading frame 10.