| Native Name: | Préfecture du Borkou-Ennedi-Tibesti |
| Conventional Long Name: | Borkou-Ennedi-Tibesti Prefecture |
| Common Name: | Borkou-Ennedi-Tibesti |
| Subdivision: | Prefecture |
| Nation: | Chad |
| Government Type: | Prefecture |
| Capital: | Faya-Largeau |
| Political Subdiv: | [1]
|
| Year Start: | 1960 |
| Year End: | 1999 |
| Event Start: | Established[2] |
| Date Start: | 13 February |
| Event End: | Disestablished |
| Date End: | 1 September |
| Event1: | End of French administration[3] |
| Date Event1: | 23 January 1965 |
| Event2: | Libyan occupation |
| Date Event2: | 1973–1987 |
| Era: | Cold War |
| Flag: | Flag of Chad |
| P1: | Borkou-Ennedi-Tibesti Region |
| Flag P1: | Flag of Chad.svg |
| S1: | Borkou Department |
| Flag S1: | Flag of Chad.svg |
| S2: | Ennedi Department |
| Flag S2: | Flag of Chad.svg |
| S3: | Tibesti Department |
| Flag S3: | Flag of Chad.svg |
| Stat Year1: | 1960 |
| Stat Area1: | 530000 |
| Stat Pop1: | 51,472 |
| Stat Year2: | 1993 |
| Stat Area2: | 600350 |
| Stat Pop2: | 73,185 |
| Footnotes: | Area and population source: |
Borkou-Ennedi-Tibesti Prefecture was the largest of the 14 prefectures of Chad between 1960 and 1999. It was transformed into Borkou-Ennedi-Tibesti Region, one of the 18 regions into which the country has been divided since 2002. Its name is often abbreviated to BET.
Located in the north of Chad it was adjacent to Algeria, while also bordering Niger and Sudan. Borkou-Ennedi-Tibesti covered an area of 600,350 km, almost half of Chad's total area. It had a population of 73,185 (as of 1993), partly nomadic and also scattered small towns and other settlements. Its capital was Faya-Largeau.
Borkou-Ennedi-Tibesti is located in the Sahara Desert and extends into the Sahel. Its diverse topography ranges from the volcanic Tibesti Mountains to the Bodélé Depression, a vast Holocene lake-bed that is one of the Earth's strongest dust storm producing regions. Overall, the territory is extremely arid.