Azra Bihorac Explained

Azra Bihorac, MD, MS (born April 2, 1965) is a Bosnian-American professor, nephrologist, and critical care intensivist who is the senior associate dean of research at the University of Florida College of Medicine[1] and the R. Glenn Davis Professor of Medicine, Surgery, Anesthesiology, and Physiology & Functional Genomics.[2] She co-founded the Intelligent Critical Care Center (IC3) research center at the University of Florida in 2021 with Parisa Rashidi.

Azra Bihorac
BornApril 2, 1965Brčko, Yugoslavia
NationalityBosnian-American
EducationUniversity of Sarajevo (MD)University of Florida (MS)
OccupationDoctor • Professor of medicine • Dean
Years active1990–Present
FieldNephrology • Intensive Care • Internal Medicine
InstitutionsUniversity of Florida Health Shands HospitalUniversity of Florida College of Medicine • Intelligent Critical Care Center (IC3)
Notable WorksBiomarkers of acute kidney injury (AKI)[3] [4] Intensive Intelligent Care Unit (I2CU)[5] [6] • MySurgeryRisk[7] [8] [9]

DeepSOFA[10] [11]

Websitehttps://ic3.center.ufl.edu/

Early life and education

Bihorac grew up near Brčko and earned her medical degree from the University of Sarajevo in 1990[12] (a year before the Yugoslav Wars began) and started working at a hospital in Brčko.[13] On April 29, 1992, weeks after the start of the Bosnian War, Bihorac fled the Bosnian genocide by escaping across the Sava river with her son, her medical degree, and 2,000 deutschmarks "sown in the underlining of [her] trench coat."[14] At 5 a.m. the following morning, the Brčko bridge massacre occurred and killed 100 civilians crossing the bridge.[15]

Residencies and fellowships in Turkey and the United States

At Marmara University in Istanbul, Turkey, Bihorac was an internal medicine resident and a nephrology fellow.

In 2000, Bihorac came to the United States as a research fellow of the International Society of Nephrology and began a nephrology training fellowship at the University of Florida College of Medicine. After completing her fellowship at the University of Florida, she remained in the United States. "I got political asylum because I couldn't go back to Turkey, couldn't go back to Bosnia," Bihorac said, "so in order to practice medicine, I had to repeat all of my training."[16]

At the University of Florida, Bihorac began a residency in internal medicine in 2003 and a fellowship in critical care medicine in 2006. She completed a Master of Science for Health Sciences in Clinical Research in 2011.

Research and writing

Since 2010, Bihorac's labs have received continuous funding from the National Institutes of Health (NIH).[17] Her research focuses on using artificial intelligence, machine learning, and deep learning to augment patient diagnostics and monitoring in intensive care medicine.[18] Some of her most well-known work involves identifying biomarkers for acute kidney injury (AKI), treatment of AKI, and AI and machine learning techniques for predicting health outcomes for critically ill patients. As of May 2023, Bihorac's most cited publication is a 2013 study on AKI biomarkers, which has 812 citations.[19]

Under Bihorac's direction, the (IC3) at the University of Florida has gained attention for developments involving the use of AI to

Bihorac has edited or contributed chapters to the following textbooks:

Bihorac's work at the University of Florida has yielded more than 200 peer-reviewed scientific articles—including Scientific Reports,[23] Nature Reviews Nephrology,[24] [25] Critical Care, PLOS ONE,[26] IEEE Journal of Biomedical and Health Informatics,[27] Annals of Surgery,[28] and JAMA Surgery[29] —and over 10,000 citations in other articles.[30]

Professional organizations

Bihorac is a Fellow of the American College of Critical Care Medicine (FCCM), a designation given to "practitioners, researchers, administrators, and educators who have made outstanding contributions to the collaborative field of critical care."[31] She is also a Fellow of the American Society of Nephrology (FASN), a designation given to members of the American Society of Nephrology "who have distinguished themselves through excellence in practice or research."[32]

Awards and honors

Personal life

Bihorac is married to surgeon Charles Hobson and lives in Gainesville, Florida, with their children.[36]

External links

Notes and References

  1. Web site: Dr. Azra Bihorac named senior associate dean for research affairs . 2023-01-31 . Doctor Gator . en-US.
  2. Web site: Azra Bihorac » Intelligent Critical Care Center (IC3) » » University of Florida . 2023-01-31 . en.
  3. Kashani . Kianoush . Al-Khafaji . Ali . Ardiles . Thomas . Artigas . Antonio . Bagshaw . Sean M. . Bell . Max . Bihorac . Azra . Birkhahn . Robert . Cely . Cynthia M. . Chawla . Lakhmir S. . Davison . Danielle L. . Feldkamp . Thorsten . Forni . Lui G. . Gong . Michelle Ng . Gunnerson . Kyle J. . 2013-02-06 . Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury . Critical Care . en . 17 . 1 . R25 . 10.1186/cc12503 . 1364-8535 . 4057242 . 23388612 . free .
  4. Bihorac . Azra . Chawla . Lakhmir S. . Shaw . Andrew D. . Al-Khafaji . Ali . Davison . Danielle L. . DeMuth . George E. . Fitzgerald . Robert . Gong . Michelle Ng . Graham . Derrel D. . Gunnerson . Kyle . Heung . Michael . Jortani . Saeed . Kleerup . Eric . Koyner . Jay L. . Krell . Kenneth . 2014-04-15 . Validation of Cell-Cycle Arrest Biomarkers for Acute Kidney Injury Using Clinical Adjudication . American Journal of Respiratory and Critical Care Medicine . en . 189 . 8 . 932–939 . 10.1164/rccm.201401-0077OC . 24559465 . 25918415 . 1073-449X.
  5. Davoudi . Anis . Malhotra . Kumar Rohit . Shickel . Benjamin . Siegel . Scott . Williams . Seth . Ruppert . Matthew . Bihorac . Emel . Ozrazgat-Baslanti . Tezcan . Tighe . Patrick J. . Bihorac . Azra . Rashidi . Parisa . 2019-05-29 . Intelligent ICU for Autonomous Patient Monitoring Using Pervasive Sensing and Deep Learning . Scientific Reports . en . 9 . 1 . 8020 . 10.1038/s41598-019-44004-w . 31142754 . 6541714 . 2019NatSR...9.8020D . 2045-2322.
  6. Davoudi . Anis . Shickel . Benjamin . Tighe . Patrick James . Bihorac . Azra . Rashidi . Parisa . 2022 . Potentials and Challenges of Pervasive Sensing in the Intensive Care Unit . Frontiers in Digital Health . 4 . 10.3389/fdgth.2022.773387 . 35656333 . 9152012 . 2673-253X . free .
  7. Bihorac . Azra . Ozrazgat-Baslanti . Tezcan . Ebadi . Ashkan . Motaei . Amir . Madkour . Mohcine . Pardalos . Panagote M. . Lipori . Gloria . Hogan . William R. . Efron . Philip A. . Moore . Frederick . Moldawer . Lyle L. . Wang . Daisy Zhe . Hobson . Charles E. . Rashidi . Parisa . Li . Xiaolin . April 2019 . MySurgeryRisk: Development and Validation of a Machine-learning Risk Algorithm for Major Complications and Death After Surgery . Annals of Surgery . en-US . 269 . 4 . 652–662 . 10.1097/SLA.0000000000002706 . 29489489 . 6110979 . 0003-4932.
  8. Ren . Yuanfang . Loftus . Tyler J. . Shickel . Benjamin . Upchurch Jr. . Gilbert R. . Rashidi . Parisa . Ozrazgat-Baslanti . Tezcan . Bihorac . Azra . May 16, 2022 . Performance of a Machine Learning Algorithm Using Electronic Health Record Data to Predict Postoperative Complications and Report on a Mobile Platform . 2023-01-31 . JAMA Network Open. 5 . 5 . e2211973 . 10.1001/jamanetworkopen.2022.11973 . 35576007 . 248812592 . 9112066 .
  9. News: Landro . Laura . Why Hospitals Still Make Serious Medical Errors—and How They Are Trying to Reduce Them . 2023-03-13 . Wall Street Journal . 12 March 2023 . en-US.
  10. Shickel . Benjamin . Loftus . Tyler J. . Adhikari . Lasith . Ozrazgat-Baslanti . Tezcan . Bihorac . Azra . Rashidi . Parisa . 2019-02-12 . DeepSOFA: A Continuous Acuity Score for Critically Ill Patients using Clinically Interpretable Deep Learning . Scientific Reports . en . 9 . 1 . 1879 . 10.1038/s41598-019-38491-0 . 30755689 . 52134035 . 2045-2322. 6372608 . 1802.10238 . 2019NatSR...9.1879S .
  11. Web site: Bennett . Doug . May 8, 2019 . DeepSOFA . 2023-01-31 . The POST . en-US.
  12. Web site: ORCID Profile: Azra Bihorac . 2023-02-16 . orcid.org.
  13. Web site: LinkedIn profile: Azra Bihorac . LinkedIn.
  14. Web site: Bihorac . Azra . June 20, 2020 . @AzraBihorac . 2023-01-31 . Twitter . en.
  15. Web site: Rovcanin . Haris . 2021-04-30 . Brcko Bridge Blast Deaths Commemorated in Bosnia . 2023-01-31 . Balkan Insight . en-US.
  16. Web site: Hills & Valleys Podcast . 2019-03-25 . Ep3: Dr. Azra Bihorac, MD, MS, on How Acute Kidney Injury Should Be Treated . 2023-01-31 . Potrero . en-US.
  17. 2022-12-20 . Q&A: Azra Bihorac . Cell Reports Medicine . en . 3 . 12 . 100836 . 10.1016/j.xcrm.2022.100836 . 36543114 . 9813827 . 2666-3791.
  18. Web site: Know It All: Where AI helps and hurts in health care . 2023-03-13 . 1A . en.
  19. SpringerCitations - Details Page . 2013 . 10.1186/cc12503 . 4057242 . 23388612 . free . Kashani . K. . Al-Khafaji . A. . Ardiles . T. . Artigas . A. . Bagshaw . S. M. . Bell . M. . Bihorac . A. . Birkhahn . R. . Cely . C. M. . Chawla . L. S. . Davison . D. L. . Feldkamp . T. . Forni . L. G. . Gong . M. N. . Gunnerson . K. J. . Haase . M. . Hackett . J. . Honore . P. M. . Hoste . E. A. . Joannes-Boyau . O. . Joannidis . M. . Kim . P. . Koyner . J. L. . Laskowitz . D. T. . Lissauer . M. E. . Marx . G. . McCullough . P. A. . Mullaney . S. . Ostermann . M. . Rimmelé . T. . Critical Care . 17 . 1 . R25 . 1 .
  20. Web site: Halliday . Maureen . February 18, 2022 . Your Health: AI and the ICU . 2023-01-31 . WILX 10 . en.
  21. Web site: High-tech hospital uses artificial intelligence in patient care . 2023-02-06 . NBC News . en.
  22. Web site: UF researchers develop tool to predict complications during surgery . 2023-01-31 . Florida Trend.
  23. Shickel . Benjamin . Loftus . Tyler J. . Ruppert . Matthew . Upchurch . Gilbert R. . Ozrazgat-Baslanti . Tezcan . Rashidi . Parisa . Bihorac . Azra . 2023-01-21 . Dynamic predictions of postoperative complications from explainable, uncertainty-aware, and multi-task deep neural networks . Scientific Reports . en . 13 . 1 . 1224 . 10.1038/s41598-023-27418-5 . 36681755 . 9867692 . 2023NatSR..13.1224S . 2045-2322.
  24. Nadim . Mitra K. . Forni . Lui G. . Mehta . Ravindra L. . Connor . Michael J. . Liu . Kathleen D. . Ostermann . Marlies . Rimmelé . Thomas . Zarbock . Alexander . Bell . Samira . Bihorac . Azra . Cantaluppi . Vincenzo . Hoste . Eric . Husain-Syed . Faeq . Germain . Michael J. . Goldstein . Stuart L. . October 15, 2020 . COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup . Nature Reviews Nephrology . en . 16 . 12 . 747–764 . 10.1038/s41581-020-00356-5 . 33060844 . 7561246 . 222415986 . 1759-507X. 2445/173871 . free .
  25. Chawla . Lakhmir S. . Bellomo . Rinaldo . Bihorac . Azra . Goldstein . Stuart L. . Siew . Edward D. . Bagshaw . Sean M. . Bittleman . David . Cruz . Dinna . Endre . Zoltan . Fitzgerald . Robert L. . Forni . Lui . Kane-Gill . Sandra L. . Hoste . Eric . Koyner . Jay . Liu . Kathleen D. . February 27, 2017 . Acute kidney disease and renal recovery: consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup . Nature Reviews Nephrology . en . 13 . 4 . 241–257 . 10.1038/nrneph.2017.2 . 28239173 . 217702946 . 1759-507X. 1854/LU-8516228 . free .
  26. Thottakkara . Paul . Ozrazgat-Baslanti . Tezcan . Hupf . Bradley B. . Rashidi . Parisa . Pardalos . Panos . Momcilovic . Petar . Bihorac . Azra . 2016-05-27 . Application of Machine Learning Techniques to High-Dimensional Clinical Data to Forecast Postoperative Complications . PLOS ONE . en . 11 . 5 . e0155705 . 10.1371/journal.pone.0155705 . 1932-6203 . 4883761 . 27232332 . 2016PLoSO..1155705T . free .
  27. Shickel . Benjamin . Tighe . Patrick James . Bihorac . Azra . Rashidi . Parisa . October 27, 2017 . Deep EHR: A Survey of Recent Advances in Deep Learning Techniques for Electronic Health Record (EHR) Analysis . IEEE Journal of Biomedical and Health Informatics . 22 . 5 . 1589–1604 . 10.1109/JBHI.2017.2767063 . 29989977 . 6043423 . 2168-2208.
  28. Ozrazgat-Baslanti . Tezcan . Loftus . Tyler J. . Mohandas . Rajesh . Wu . Quran . Brakenridge . Scott . Brumback . Babette . Efron . Philip A. . Anton . Stephen . Moore . Frederick A. . Moldawer . Lyle L. . Segal . Mark S. . Bihorac . Azra . June 2022 . Clinical Trajectories of Acute Kidney Injury in Surgical Sepsis: A Prospective Observational Study . Annals of Surgery . en-US . 275 . 6 . 1184–1193 . 10.1097/SLA.0000000000004360 . 33196489 . 8116352 . 0003-4932.
  29. Loftus . Tyler J. . Tighe . Patrick J. . Filiberto . Amanda C. . Efron . Philip A. . Brakenridge . Scott C. . Mohr . Alicia M. . Rashidi . Parisa . Upchurch . Gilbert R. Jr . Bihorac . Azra . 2020-02-01 . Artificial Intelligence and Surgical Decision-making . JAMA Surgery . 155 . 2 . 148–158 . 10.1001/jamasurg.2019.4917 . 31825465 . 7286802 . 2168-6254.
  30. Web site: ResearchGate: Azra Bihorac profile .
  31. Web site: SCCM American College of Critical Care Medicine . 2023-01-31 . Society of Critical Care Medicine (SCCM).
  32. Web site: Nesbitt . Hal . American Society of Nephrology Member Services - FASN . 2023-01-31 . www.asn-online.org . en-us.
  33. Web site: VIVO Azra Bihorac . VIVO: University of Florida.
  34. Web site: Loop Azra Bihorac . 2023-02-16 . loop.frontiersin.org.
  35. Web site: Ivanov . Danielle . March 31, 2022 . AOA Honor Medical Society celebrates new members . 2023-02-16 . Doctor Gator . en-US.
  36. Web site: Bihorac . Azra . Kidney Love . 2023-02-16 . Kidney Love: Azra Bihorac website . en.

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