Azirinomycin Explained

Azirinomycin is an antibiotic azirine derivative with the molecular formula C₄H₅NO₂ which is produced by the bacterium Streptomyces aureus.^{[1] [2]} Azirinomycin was first isolated in 1971.^[3] Azirinomycin is toxic and therefore it cannot not be used in human medicine.^[3]

Further reading

• Miller . TW . Tristram . EW . Wolf . FJ . Azirinomycin. II. Isolation and chemical characterization as 3-methyl-2(2H) azirinecarboxylic acid. . The Journal of Antibiotics . January 1971 . 24 . 1 . 48–50 . 10.7164/antibiotics.24.48 . 5541332. free .
• Stapley . EO . Hendlin . D . Jackson . M . Miller . AK . Hernandez . S . Mata . JM . Azirinomycin. I. Microbial production and biological characteristics. . The Journal of Antibiotics . January 1971 . 24 . 1 . 42–7 . 10.7164/antibiotics.24.42 . 5541331. free .
• Book: Williams . R. M. . Synthesis of Optically Active Alpha-Amino Acids . 22 October 2013 . Elsevier . 978-1-4832-9295-3 . 126 . en.
• Book: Carreira . Erick M. . Science of Synthesis Knowledge Updates 2011 Vol. 3 . 14 May 2014 . Georg Thieme Verlag . 978-3-13-178751-4 . 137 . en.

Notes and References

1. Web site: Communications . EBCONT . Azirinomycin . roempp.thieme.de .
2. Stapley . Edward O. . Hendlin . David . Jackson . Marion . Miller . A. Kathrine . Hernandez . Sebastian . Mata . Justo M. . Azirinomycin. I . The Journal of Antibiotics . 25 January 1971 . 24 . 1 . 42–47 . 10.7164/antibiotics.24.42 . en . 0021-8820. free .
3. Book: Diana . Patrizia . Cirrincione . Girolamo . Biosynthesis of Heterocycles: From Isolation to Gene Cluster . 30 January 2015 . John Wiley & Sons . 978-1-118-96042-4 . 101 . en.