Azalanstat Explained

Azalanstat (INN,[1] codenamed RS-21607) is an anti-obesity drug acting as a lanosterol 14α-demethylase inhibitor.[2] [3]

Notes and References

  1. Web site: International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names (Rec. INN): List 36 . World Health Organization . 3 January 2017 . 141.
  2. Walker KA, Kertesz DJ, Rotstein DM, Swinney DC, Berry PW, So OY, Webb AS, Watson DM, Mak AY, Burton PM . 6 . Selective inhibition of mammalian lanosterol 14 alpha-demethylase: a possible strategy for cholesterol lowering . Journal of Medicinal Chemistry . 36 . 15 . 2235–7 . July 1993 . 8340925 . 10.1021/jm00067a022 .
  3. Burton PM, Swinney DC, Heller R, Dunlap B, Chiou M, Malonzo E, Haller J, Walker KA, Salari A, Murakami S . 6 . Azalanstat (RS-21607), a lanosterol 14 alpha-demethylase inhibitor with cholesterol-lowering activity . Biochemical Pharmacology . 50 . 4 . 529–44 . August 1995 . 7646560 . 10.1016/0006-2952(95)00152-p .

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