| Ayzac-Ost | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Ayzac-Ost (65).svg |
| Arrondissement: | Argelès-Gazost |
| Canton: | La Vallée des Gaves |
| Insee: | 65056 |
| Postal Code: | 65400 |
| Mayor: | Serge Cabar[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | CC Pyrénées Vallées des Gaves |
| Coordinates: | 43.0247°N -0.0953°W |
| Elevation M: | 416 |
| Elevation Min M: | 408 |
| Elevation Max M: | 850 |
| Area Km2: | 3.08 |
Ayzac-Ost (pronounced as /fr/; Occitan (post 1500);: Aisac e Òst) is a commune in the Hautes-Pyrénées department of southwestern France.