Avacincaptad pegol explained
| Tradename: | Izervay |
| Dailymedid: | Avacincaptad pegol |
| Routes Of Administration: | Intravitreal |
| Class: | Complement inhibitor |
| Atc Prefix: | None |
| Legal Us: | Rx-only |
| Legal Us Comment: | [1] |
| Cas Number: | 1613641-69-2 |
| Drugbank: | DB15165 |
| Unii: | TT0V5JLG5B |
| Kegg: | D11748 |
| Synonyms: | Zimura |
| C: | 395 |
| H: | 453 |
| F: | 21 |
| N: | 142 |
| Na: | 39 |
| O: | 262 |
| P: | 39 |
Avacincaptad pegol, sold under the brand name Izervay, is a medication used for the treatment of age-related macular degeneration. Avacincaptad pegol is a complement inhibitor.
Avacincaptad pegol was approved for medical use in the United States in August 2023.[2] [3] [4]
Medical uses
Avacincaptad pegol is indicated for the treatment of geographic atrophy secondary to age-related macular degeneration.[5]
Society and culture
Avacincaptad pegol is the international nonproprietary name.[6]
Notes and References
- Web site: Izervay- avacincaptad pegol injection . DailyMed . 9 August 2023 . 25 August 2023 . 26 August 2023 . https://web.archive.org/web/20230826065238/https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1642fe6a-dc26-4d20-ae6e-654af744e3bd . live .
- Web site: Novel Drug Approvals for 2023 . U.S. Food and Drug Administration (FDA) . 18 August 2023 . 25 August 2023 . 21 January 2023 . https://web.archive.org/web/20230121035617/https://www.fda.gov/drugs/new-drugs-fda-cders-new-molecular-entities-and-new-therapeutic-biological-products/novel-drug-approvals-2023 . live .
- Iveric Bio Receives U.S. FDA Approval for Izervay (avacincaptad pegol intravitreal solution), a New Treatment for Geographic Atrophy . Astellas Pharma Inc. . PR Newswire . 4 August 2023 . 25 August 2023 . 26 August 2023 . https://web.archive.org/web/20230826063111/https://www.prnewswire.com/news-releases/iveric-bio-receives-us-fda-approval-for-izervay-avacincaptad-pegol-intravitreal-solution-a-new-treatment-for-geographic-atrophy-301894042.html . live .
- Kang C . Avacincaptad Pegol: First Approval . Drugs . 83 . 15 . 1447–1453 . October 2023 . 37814173 . 10.1007/s40265-023-01948-8 . 263801918 . 18 December 2023 . 27 April 2024 . https://web.archive.org/web/20240427134435/https://figshare.com/articles/online_resource/Avacincaptad_Pegol_First_Approval/24123651 . live .
- Web site: Drug Approval Package: Izervay . U.S. Food and Drug Administration (FDA) . 1 September 2023 . 20 November 2023 . 20 November 2023 . https://web.archive.org/web/20231120061523/https://www.accessdata.fda.gov/drugsatfda_docs/nda/2023/217225Orig1s000TOC.cfm . live .
- ((World Health Organization)) . International nonproprietary names for pharmaceutical substances (INN): recommended INN: list 75 . WHO Drug Information . 30 . 1 . 2016 . 10665/331046 . free . World Health Organization .
