| Honorific-Prefix: | The Honourable |
| Augustine Colin Macdonald | |
| Order: | 10th |
| Office: | Lieutenant Governor of Prince Edward Island |
| Term Start: | June 2, 1915 |
| Term End: | July 16, 1919 |
| Predecessor: | Benjamin Rogers |
| Successor: | Murdock MacKinnon |
| Governor General: | The Duke of Connaught and Strathearn The Duke of Devonshire |
| Premier: | John Alexander Mathieson Aubin E. Arsenault |
| Office1: | Member of the General Assembly of Prince Edward Island for 3rd Kings |
| Predecessor1: | None |
| Successor1: | Lemuel Owen |
| Term Start1: | April 19, 1870 |
| Term End1: | April 24, 1873 |
| Constituency Mp2: | King's County |
| Parliament2: | Canadian |
| Alongside2: | Daniel Davies, |
| Term Start2: | September 29, 1873 |
| Term End2: | January 22, 1874 |
| Alongside3: | Ephraim Bell Muttart |
| Predecessor3: | Peter Adolphus McIntyre |
| Successor3: | James Edwin Robertson |
| Term Start3: | September 17, 1878 |
| Term End3: | June 20, 1882 |
| Alongside4: | Peter Adolphus McIntyre |
| Predecessor4: | James Edwin Robertson |
| Successor4: | James Edwin Robertson Peter Adolphus McIntyre |
| Term Start4: | April 26, 1883 |
| Term End4: | February 22, 1887 |
| Alongside5: | John McLean (Canadian politician) |
| Predecessor5: | James Edwin Robertson Peter Adolphus McIntyre |
| Successor5: | The electoral district was abolished in 1892. |
| Term Start5: | March 5, 1891 |
| Term End5: | June 23, 1896 |
| Constituency Mp6: | King's |
| Parliament6: | Canadian |
| Predecessor6: | The electoral district was created in 1892. |
| Successor6: | James Joseph Hughes |
| Term Start6: | June 23, 1896 |
| Term End6: | November 7, 1900 |
| Birth Date: | 30 June 1837 |
| Birth Place: | Panmure Island, Prince Edward Island Colony |
| Death Place: | Charlottetown, Prince Edward Island, Dominion of Canada |
| Nationality: | Canadian |
| Party: | Liberal-Conservative |
| Relations: | Andrew Archibald (brother) Archibald John (brother) John S. MacDonald (father-in-law) |
| Children: | M. Josephine, W. Jane, S. Francis, C. Helena, A. Florence, and A. J. Louis |
| Residence: | Panmure Island, Prince Edward Island Montague, Prince Edward Island |
| Alma Mater: | University of Prince Edward Island |
| Occupation: | merchant |
| Profession: | Politician |
Augustine Colin Macdonald (June 30, 1837 - July 16, 1919) was a Canadian merchant and political figure. He represented King's County and later King's in the House of Commons of Canada from 1873 to 1874, from 1878 to 1882, from 1883 to 1887 and from 1891 to 1900 as a Liberal-Conservative member. Macdonald served as the tenth Lieutenant Governor of Prince Edward Island from 1915 to 1919.
He was born in Panmure Island, the son of Hugh Macdonald, a Scottish immigrant, and was educated in Georgetown and Charlottetown. Macdonald married Mary Elizabeth, the daughter of John Small MacDonald, in 1865. He served as a captain in the militia. He represented 3rd Kings in the Legislative Assembly of Prince Edward Island from 1870 to 1873. He resigned his seat in 1873 to run for the federal seat. On June 2, 1915, Macdonald was named Lieutenant Governor. He died in office in 1919.
His brother Andrew Archibald served in the Senate of Canada and was also a Lieutenant Governor for the province and his brother Archibald John was a long-time member of the provincial assembly.