August Wilhelm Karl Knobel (7 February 1807 - 25 May 1863) was a German Protestant theologian born in Tzschecheln near Sorau, Niederlausitz.
From 1826 he studied philosophy, philology and theology at the University of Breslau, earning his doctorate in 1831. Afterwards, he became a lecturer, and later an associate professor (1835) at Breslau. In 1838 he became a professor of theology at Breslau, and shortly afterwards relocated to the University of Giessen.
Knobel specialized in Old Testament exegesis, and was the author of numerous interpretations and commentaries on the Pentateuch and other books of the Old Testament. Among his better-known publications are the following:
The commentaries upon Isaiah and the books of the Pentateuch were rewritten by August Dillmann.