Atrolysin F Explained

Atrolysin F
Ec Number:3.4.24.45
Cas Number:172306-52-4

Atrolysin F (Crotalus atrox metalloendopeptidase, hemorrhagic toxin f, Crotalus atrox metalloendopeptidase f) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Cleavage of Val2-Asn, Gln4-His, Leu6-Cys, His10-Leu, Ala14-Leu and Tyr16-Leu bonds in insulin B chain

This endopeptidase is present in the venom of the western diamondback rattlesnake (Crotalus atrox).

Notes and References

  1. Nikai T, Mori N, Kishida M, Sugihara H, Tu AT . Isolation and biochemical characterization of hemorrhagic toxin f from the venom of Crotalus atrox (western diamondback rattlesnake) . Archives of Biochemistry and Biophysics . 231 . 2 . 309–19 . June 1984 . 6375570 . 10.1016/0003-9861(84)90393-x .

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