The men's 4 × 400 metres relay event at the 2015 African Games was held on 16 and 17 September.
| width=200 valign=top | Raymond Kibet Alex Sampao Kiprono Koskei Boniface Mweresa | width=200 valign=top | Onkabetse Nkobolo Nijel Amos Leaname Maotoanong Isaac Makwala | width=200 valign=top | Miloud Laradt Miloud Rahmani Sofiane Bouhedda Abdelmalik Lahoulou |
Qualification: First 3 teams of each heat (Q) plus the next 2 fastest (q) qualified for the final.[1]
| Rank | Heat | Nation | Athletes | Time | Notes | |
|---|---|---|---|---|---|---|
| 1 | 1 | 3:04.72 | Q | |||
| 2 | 1 | 3:05.55 | Q | |||
| 3 | 2 | 3:07.33 | Q | |||
| 4 | 2 | 3:08.23 | Q | |||
| 5 | 2 | 3:09.12 | Q | |||
| 6 | 2 | 3:10.25 | q | |||
| 7 | 1 | 3:10.73 | Q | |||
| 8 | 1 | 3:12.07 | q | |||
| 9 | 2 | 3:13.16 | SB | |||
| 10 | 1 | 3:18.86 | SB | |||
| 1 |
| Rank | Nation | Athletes | Time | Notes | |
|---|---|---|---|---|---|
| 3:00.34 | GR | ||||
| 3:00.95 | NR | ||||
| 3:03.07 | |||||
| 4 | 3:03.52 | ||||
| 5 | 3:05.15 | ||||
| 6 | 3:07.73 | ||||
| 7 | 3:09.75 | ||||
| 8 | 3:11.53 |