| Event: | Men's 400 metres |
| Games: | 2010 Asian Games |
| Venue: | Aoti Main Stadium |
| Dates: | 21–22 November |
| Competitors: | 18 |
| Nations: | 11 |
| Gold: | Femi Ogunode |
| Goldnoc: | QAT |
| Silver: | Yuzo Kanemaru |
| Silvernoc: | JPN |
| Bronze: | Yousef Masrahi |
| Bronzenoc: | KSA |
| Prev: | 2006 |
| Next: | 2014 |
See main article: Athletics at the 2010 Asian Games. The men's 400 metres event at the 2010 Asian Games was held at the Aoti Main Stadium, Guangzhou, China on 21–22 November.
All times are China Standard Time
| width=220 | Date | width=50 | Time | width=150 | Event |
|---|---|---|---|---|---|
| Sunday, 21 November 2010 | 19:05 | Round 1 | |||
| Monday, 22 November 2010 | 18:00 | Final |
| width=40 | Rank | width=250 | Athlete | width=80 | Time | width=50 | Notes |
|---|---|---|---|---|---|---|---|
| 1 | 46.25 | Q | |||||
| 2 | 46.35 | Q | |||||
| 3 | 46.66 | q | |||||
| 4 | 46.75 | ||||||
| 5 | 48.09 | ||||||
| — | DSQ |
| width=40 | Rank | width=250 | Athlete | width=80 | Time | width=50 | Notes |
|---|---|---|---|---|---|---|---|
| 1 | 46.33 | Q | |||||
| 2 | 46.76 | Q | |||||
| 3 | 46.80 | ||||||
| 4 | 46.93 | ||||||
| 5 | 47.06 | ||||||
| 6 | 48.29 |
| width=40 | Rank | width=250 | Athlete | width=80 | Time | width=50 | Notes |
|---|---|---|---|---|---|---|---|
| 1 | 45.48 | Q | |||||
| 2 | 45.64 | Q | |||||
| 3 | 46.58 | q | |||||
| 4 | 47.77 | ||||||
| 5 | 48.91 | ||||||
| — | DSQ |
| width=40 | Rank | width=250 | Athlete | width=80 | Time | width=50 | Notes |
|---|---|---|---|---|---|---|---|
| 45.12 | |||||||
| 45.32 | |||||||
| 45.71 | |||||||
| 4 | 46.34 | ||||||
| 5 | 46.65 | ||||||
| 6 | 47.05 | ||||||
| 7 | 47.11 | ||||||
| 8 | 47.49 |