The men's 4 x 100 metres relay at the 2007 All-Africa Games was held on July 19–20.
| width=200 valign=top | Isaac Uche Obinna Metu Chinedu Oriala Olusoji Fasuba | width=200 valign=top | Morné Nagel Leigh Julius Lee Roy Newton Sherwin Vries | width=200 valign=top | Ngonidzashe Makusha Gabriel Mvumvure Brian Dzingai Lewis Banda |
Qualification: First 3 teams of each heat (Q) plus the next 2 fastest (q) qualified for the final.
| Rank | Heat | Nation | Athletes | Time | Notes | |
|---|---|---|---|---|---|---|
| 1 | 39.07 | Q | ||||
| 1 | 39.33 | Q, NR | ||||
| 2 | 39.49 | Q | ||||
| 1 | 39.54 | Q | ||||
| 2 | 39.54 | Q | ||||
| 2 | 39.92 | Q | ||||
| 2 | 39.93 | q, NR | ||||
| 1 | 40.56 | q | ||||
| 1 | 41.11 | NR | ||||
| 10 | 1 | 41.61 | ||||
| 1 | ||||||
| 2 | ||||||
| 2 |
| Rank | Nation | Athletes | Time | Notes | |
|---|---|---|---|---|---|
| 38.91 | |||||
| 39.11 | |||||
| 39.16 | NR | ||||
| 4 | 39.59 | ||||
| 5 | 39.64 | ||||
| 6 | 40.07 | ||||
| 7 | 40.17 | NR | |||