| Official Name: | Assis Brasil |
| Settlement Type: | Municipality |
| Pushpin Map: | Brazil |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location in Brazil |
| Subdivision Type: | Country |
| Subdivision Name: | Brazil |
| Subdivision Type1: | State |
| Subdivision Name1: | Acre |
| Leader Title: | Mayor |
| Leader Name: | Antonio Barbosa de Sousa (PSDB) |
| Area Total Km2: | 4974 |
| Population As Of: | 2020 est |
| Population Total: | 7,534 |
| Population Blank1 Title: | Ethnicities |
| Timezone: | ACT |
| Utc Offset: | -5 |
| Coordinates: | -10.9408°N -69.5669°W |
Assis Brasil (pronounced as /pt-BR/) is a municipality located in the south of the Brazilian state of Acre. Its population is 7,534 (2020 est) and its area is .
The municipality contains part of the Rio Acre Ecological Station.It also contains part of the Chico Mendes Extractive Reserve, a sustainable use environmental unit created in 1990.
It is located near the Brazil–Peru Integration Bridge.
The municipality was named after Joaquim Francisco de Assis Brasil, a diplomat who was involved in the transference of Acre from Bolivian to Brazilian control after the Acre War.