Ascopyrone tautomerase explained

Ascopyrone tautomerase
Ec Number:	5.3.2.7

In enzymology, an ascopyrone tautomerase is an enzyme that catalyzes the chemical reaction

1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose

\rightleftharpoons 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose

Hence, this enzyme has one substrate, 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose, and one product, 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose.

The enzyme is involved with the anhydrofructose pathway.^[1]

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting keto- and enol-groups. The systematic name of this enzyme class is 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose Delta3-Delta1-isomerase. Other names in common use include ascopyrone isomerase, ascopyrone intramolecular oxidoreductase, 1,5-anhydro-D-glycero-hex-3-en-2-ulose tautomerase, APM tautomerase, ascopyrone P tautomerase, and APTM.

See also

• Anhydrofructose pathway
• 1,5-anhydro-D-fructose dehydratase
• exo-(1→4)-α-D-glucan lyase

References

• Yu S, Refdahl C, Lundt I . 2004 . Enzymatic description of the anhydrofructose pathway of glycogen degradation; I. Identification and purification of anhydrofructose dehydratase, ascopyrone tautomerase and alpha-1,4-glucan lyase in the fungus Anthracobia melaloma . Biochim. Biophys. Acta . 1672 . 120 - 9 . 15110094 . 2 . 10.1016/j.bbagen.2004.03.004 .
• Yu S, Fiskesund R . 2006 . The anhydrofructose pathway and its possible role in stress response and signaling . Biochim. Biophys. Acta . 1760 . 1314 - 22 . 16822618 . 9 . 10.1016/j.bbagen.2006.05.007 .

Notes and References

1. IUBMB - Anhydrofructose Pathway