| Type: | Bishop |
| Honorific-Prefix: | Most Reverend |
| Ascanio Maffei | |
| Archbishop of Urbino | |
| Church: | Catholic Church |
| Archdiocese: | Archdiocese of Urbino |
| Term: | 1646–1659 |
| Predecessor: | Francesco Vitelli |
| Successor: | Giacomo de Angelis |
| Consecration: | 1 Jul 1646 |
| Consecrated By: | Marcello Lante della Rovere |
| Birth Place: | Rome, Italy |
| Death Date: | Oct 1659 |
Ascanio Maffei (died 1659) was a Roman Catholic prelate who served as Archbishop of Urbino (1646–1659).[1]
Ascanio Maffei was born in Rome, Italy.[2] On 25 Jun 1646, he was appointed during the papacy of Pope Innocent X as Archbishop of Urbino.On 1 Jul 1646, he was consecrated bishop by Marcello Lante della Rovere, Cardinal-Bishop of Ostia e Velletri, with Ranuccio Scotti Douglas, Bishop Emeritus of Borgo San Donnino, and Giacomo Accarisi, Bishop of Vieste, serving as co-consecrators. He served as Archbishop of Urbino until his death in Oct 1659.
While bishop, he was the principal co-consecrator of Flavio Galletti, Bishop of Anglona-Tursi (1646) .