| Honorific-Prefix: | Most Reverend |
| Ascanio Gesualdo | |
| Archbishop of Bari (-Canosa) | |
| Church: | Catholic Church |
| Diocese: | Archdiocese of Bari-Canosa |
| Term: | 1613–1638 |
| Predecessor: | Decio Caracciolo Rosso |
| Successor: | Diego Sersale |
| Death Date: | 27 January 1638 |
| Death Place: | Bari, Italy |
Ascanio Gesualdo (died 27 January 1638) was a Roman Catholic prelate who served as Archbishop of Bari (1613–1638), Titular Patriarch of Constantinople (1618–1638), and Apostolic Nuncio to the Emperor (1617–1621).[1]
Gesualdo was born in Naples in the later sixteenth century, the son of Michele Gesualdo and Maria Caracciolo. In 1609 he became a referendary of the Apostolic Signatura.[2]
On 1 July 1613, during the papacy of Pope Paul V, he was appointed to the Archdiocese of Bari-Canosa. On 21 October 1615 he was appointed papal nuncio to the Brussels court of the Archdukes Albert and Isabella.[3] On 17 June 1617, he was transferred to Prague as Apostolic Nuncio to the Emperor.
On 25 June 1618, he was appointed by Pope Paul V as Titular Patriarch of Constantinople. On 17 April 1621, he resigned as imperial nuncio. He arrived in Bari on 19 March 1622 and dedicated himself full-time to his duties as Bishop of Bari. He held diocesan synods in 1624 and 1628.[2] He remained Titular Patriarch of Constantinople until his death on 27 January 1638.
He died in Bari, where he was buried in the cathedral.