| Asante Akim South Municipal District | |
| Settlement Type: | Municipal District |
| Pushpin Map: | Ghana |
| Pushpin Map Caption: | Location of Asante Akim South Municipal District within Ashanti |
| Subdivision Type: | Country |
| Subdivision Type1: | Region |
| Subdivision Type2: | Capital |
| Subdivision Name2: | Juaso |
| Leader Title: | Municipal Chief Executive |
| Leader Name: | Mr. Alexander Frimpong |
| Area Total Km2: | 1275 |
| Population As Of: | 2021 |
| Population Total: | 123,633 |
| Population Density Km2: | auto |
| Timezone: | GMT |
| Utc Offset: | +0 |
| Coordinates: | 6.5667°N -8°W |
Asante Akim South Municipal District is one of the forty-three districts in Ashanti Region, Ghana. Originally created as an ordinary district assembly in 1988 as Asante Akim South District, which it was created from the former Asante Akim District Council. Later it was elevated to municipal district assembly status on 15 March 2018. The municipality is located in the eastern part of Ashanti Region and has Juaso as its capital town.