Arvinder Singh Soin Explained

Arvinder Singh Soin
Birth Date:1963 1, df=yes
Birth Place:Birmingham, United Kingdom
Nationality:Indian
Education:MBBS (AIIMS), MS (AIIMS), FRCS (Edin), FRCS (Glas), FRCS (Transplant Surgery) - Cambridge, UK
Known For:Pioneering Liver Transplantation, Transplant surgery, Living donor liver transplantation (LDLT)
Module:
Profession:Hepatobiliary and Liver Transplant Surgeon
Work Institutions:Medanta-The Medicity,
Sir Gangaram Hospital
Specialism:Pioneer in Liver Transplantation,
Transplant surgery,
Living donor liver transplantation (LDLT)
Research Field:Research in transplantation, University of Cambridge
Prizes:Padma Shri, RD Birla National Award, Swasth Bharat Samman Award- Zee TV, MSOSA Award for Excellence, Medical Statesman of the Year (2012) E-MEDINEWS AWARDS

Dr. Arvinder Singh Soin is the Chief Hepatobiliary and Liver Transplant Surgeon & Chairman of the Institute of Liver Transplantation and Regenerative Medicine, Medanta-The Medicity, India. [1] A surgeon and pioneer in the field of liver transplantation, acknowledged for his work in establishing liver transplantation in India. Dr. Soin also runs the Liver Transplant institute at the Sir H. N. Reliance Foundation Hospital, Mumbai. Dr Soin has performed more than 3500 living donor liver transplants in India,[2] which is the highest in the country, and the second-highest in the world.

Early life and education

Arvinder Singh Soin was born in Birmingham, United Kingdom in the year 1963. He went on to study medicine and surgery from India and UK. An alumnus of the All India Institute of Medical Sciences, New Delhi, where he spent 11 years gaining his MBBS and MS degrees. After which he pursued further studies to gain specialist experience in Liver and Gastrointestinal Surgery, during which he worked on the research thesis of Portal Hypertensive Gastropathy. Further, he also obtained FRCS (Fellowship of the Royal Colleges of Surgeons) degrees from both Glasgow and Edinburgh in the UK. [3]

Dr Soin was one of the first few surgeons in the UK to qualify for and obtain an Intercollegiate FRCS in Transplant Surgery. He trained and worked at the University of Cambridge for 5 years and the University of Birmingham for a year for Liver and Biliary Surgery, Liver, Kidney, Small Bowel and Pancreas transplantation.

Professional experience

From 2001 to 2010, he established a humongous liver transplant centre at Sir Gangaram Hospital. In June 2010, he moved with his entire team to Medanta-The Medicity, Gurgaon (Delhi-NCR), where he established a 150-bedded (including 36 Liver ICU beds) dedicated Liver Treatment facility, carrying out 250 liver transplants and hundreds of complex liver and biliary tract surgeries every year.

Research

Dr A S Soin is recognized for his pioneering research in the field of liver transplantation and establishing Liver Transplantation in India in 1998 when he performed the country’s first successful transplant. At Cambridge, he conducted successful research in transplantation, for which more than 110 of his original research papers and book contributions have been published in international and national journals & books.

Faculty and speaker

Recognitions

  1. Awarded Padma Shri by the President of India in 2010 for pioneering the development in Liver Transplantation in India. [4]
  2. Awarded the RD Birla Outstanding Clinician of the Year Award for the year 2010 [5]
  3. Awarded the Zee TV - Swasth Bharat Samman Award for pioneering Liver Transplantation, 2011
  4. Medical Statesman of the Year - E-MEDINEWS AWARDS, 2012
  5. MSOSA Award for Excellence, 2014

Breakthrough cases

Publications

  1. Soin AS; Efficacy and safety of everolimus with reduced tacrolimus in living-donor liver transplant recipients: 12-month results of a randomized multicenter study Jun 2018[21]
  2. Soin AS; An international multicenter study of protocols for liver transplantation during a pandemic: A case for quadripartite equipoise Oct 2020[22]
  3. Soin AS; Identification of an Upper Limit of Tumor Burden for Downstaging in Candidates with Hepatocellular Cancer Waiting for Liver Transplantation: A West-East Collaborative Effort Feb 2020[23]
  4. Soin AS; Evaluation of the Intention-to-Treat Benefit of Living Donation in Patients With Hepatocellular Carcinoma Awaiting a Liver Transplant Sept 2021[24]
  5. Soin AS; Liver Transplant Outcomes in India Jan 2022[25]
  6. Soin AS; Restructuring Living-Donor Liver Transplantation at a High-Volume Center During the COVID-19 Pandemic Aug 2021[26]
  7. Soin AS; Extrahepatic Malignancies and Liver Transplantation: Current Status Aug 2021[27]
  8. Soin AS; De Novo Malignancy After Living Donor Liver Transplantation: A Large Volume Experience Oct 2020[28]
  9. Soin AS; Experience With LDLT in Patients With Hepatocellular Carcinoma and Portal Vein Tumor Thrombosis Postdownstaging Nov 2020[29]
  10. Soin AS; Outcome of hepatitis C-related liver transplantation in direct-acting antiviral era Dec 2020[30]
  11. Soin AS; Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis Aug 2021[31]
  12. Soin AS; Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific association for the study of the liver (APASL): an update

July 2019[32]

  1. Soin AS; Liver Transplantation for Hepatocellular Carcinoma. Working Group Report from the ILTS Transplant Oncology Consensus Conference

Jun 2020[33]

  1. Soin AS; Tocilizumab plus standard care versus standard care in patients in India with moderate to severe COVID-19-associated cytokine release syndrome (COVINTOC): an open-label, multicentre, randomised, controlled, phase 3 trial May 2021[34]
  2. Soin AS, Amanjit Singh; Recanalized umbilical vein as a conduit for anterior sector venous outflow reconstruction in right lobe grafts. Surgery. 2007 Jun;141(6):830. Epub 2007 Apr 17.[35]
  3. Varma V, Gupta S, Soin A, Nundy S. Does the presence of a lump or jaundice in a patient with gall bladder cancer mean the lesion is not respectable. Dig Surg 2009; 26:306-311[36]

External links

Notes and References

  1. Web site: Dr. AS Soin, Chairman of Liver Transplantation and Regenerative Medicine . 2021-05-29.
  2. Web site: Dr. AS Soin - ILTS 2021 . 2021-05-29.
  3. Web site: Liver Transplant Surgery . 2021-05-29.
  4. Web site: Padma Awards . Ministry of Home Affairs, Government of India . 2015 . 21 July 2015 . dead . https://web.archive.org/web/20151015193758/http://mha.nic.in/sites/upload_files/mha/files/LST-PDAWD-2013.pdf . 15 October 2015 . dmy .
  5. Web site: Dr Arvinder Singh Soin honoured with R D Birla Award . India Medical Times . 2011 . 21 July 2018 . dmy .
  6. Web site: Padma Shri Dr Arvinder Singh Soin gets RD Birla National Award . 2021-06-08.
  7. Web site: India's First Successful Pediatric Liver Transplant . 2021-06-08.
  8. Web site: Liver transplant gives new lease of life to 9-year-old . 2021-06-08.
  9. News: Pak boy receives first bloodless liver transplant . . 28 April 2005 . 2021-06-08.
  10. Web site: A challenging problem . 2021-06-08.
  11. News: Pak boy youngest to have liver transplant . . 3 August 2006 . 2021-06-08.
  12. News: 78-yr-old man is oldest to undergo liver transplant . . 18 July 2011 . 2021-06-08.
  13. News: Sons donate half a liver each to dad . . 21 March 2008 . 2021-06-08.
  14. Web site: Domino effect: Two toddlers cured with one donor liver . 20 February 2009 . 2021-06-08.
  15. News: Rare liver surgeries on kids . . 20 February 2009 . 2021-06-08.
  16. Web site: 2-Month-Old Nigerian Baby Undergoes Liver Transplant In Delhi . 24 October 2016 . 2021-06-08.
  17. News: India's first successful swap lung transplant performed at Ganga Ram Hospital . . 20 August 2009 . 2021-06-08.
  18. News: Nigerian infant, Indian in swap liver transplants . . 20 August 2009 . 2021-06-08.
  19. Web site: Six simultaneous liver transplants save lives of 3 kids . 18 January 2012 . 2021-06-08.
  20. News: Software engineer gets first successful intestinal transplant . . 20 August 2009 . 2021-06-08.
  21. Efficacy and safety of everolimus with reduced tacrolimus in living-donor liver transplant recipients: 12-month results of a randomized multicenter study . 2018 . 29237235 . Jeng . L. B. . Lee . S. G. . Soin . A. S. . Lee . W. C. . Suh . K. S. . Joo . D. J. . Uemoto . S. . Joh . J. . Yoshizumi . T. . Yang . H. R. . Song . G. W. . Lopez . P. . Kochuparampil . J. . Sips . C. . Kaneko . S. . Levy . G. . American Journal of Transplantation . 18 . 6 . 1435–1446 . 10.1111/ajt.14623 . free .
  22. An international multicenter study of protocols for liver transplantation during a pandemic: A case for quadripartite equipoise . 2020 . 32454041 . Chew . C. A. . Iyer . S. G. . Kow AWC . Madhavan . K. . Wong AST . Halazun . K. J. . Battula . N. . Scalera . I. . Angelico . R. . Farid . S. . Buchholz . B. M. . Rotellar . F. . Chan . A. C. . Kim . J. M. . Wang . C. C. . Pitchaimuthu . M. . Reddy . M. S. . Soin . A. S. . Derosas . C. . Imventarza . O. . Isaac . J. . Muiesan . P. . Mirza . D. F. . Bonney . G. K. . Journal of Hepatology . 73 . 4 . 873–881 . 10.1016/j.jhep.2020.05.023 . 7245234 .
  23. Identification of an Upper Limit of Tumor Burden for Downstaging in Candidates with Hepatocellular Cancer Waiting for Liver Transplantation: A West-East Collaborative Effort . 2020 . 32075133 . Lai . Q. . Vitale . A. . Halazun . K. . Iesari . S. . Viveiros . A. . Bhangui . P. . Mennini . G. . Wong . T. . Uemoto . S. . Lin . C. C. . Mittler . J. . Ikegami . T. . Zhe . Y. . Zheng . S. S. . Soejima . Y. . Hoppe-Lotichius . M. . Chen . C. L. . Kaido . T. . Lo . C. M. . Rossi . M. . Soin . A. S. . Finkenstedt . A. . Emond . J. C. . Cillo . U. . Lerut . J. . Cancers . 12 . 2 . 452 . 10.3390/cancers12020452 . 7072306 . free .
  24. Evaluation of the Intention-to-Treat Benefit of Living Donation in Patients With Hepatocellular Carcinoma Awaiting a Liver Transplant . 2021 . 34259797 . Lai . Q. . Sapisochin . G. . Gorgen . A. . Vitale . A. . Halazun . K. J. . Iesari . S. . Schaefer . B. . Bhangui . P. . Mennini . G. . Wong TCL . Uemoto . S. . Lin . C. C. . Mittler . J. . Ikegami . T. . Yang . Z. . Frigo . A. C. . Zheng . S. S. . Soejima . Y. . Hoppe-Lotichius . M. . Chen . C. L. . Kaido . T. . Lo . C. M. . Rossi . M. . Soin . A. S. . Finkenstedt . A. . Emond . J. C. . Cillo . U. . Lerut . J. P. . JAMA Surgery . 156 . 9 . e213112 . 10.1001/jamasurg.2021.3112 . 8281041 .
  25. Liver Transplant Outcomes in India . 2022 . 35106148 . Choudhary . N. S. . Bhangui . P. . Soin . A. S. . Clinical Liver Disease . 19 . 1 . 32–35 . 10.1002/cld.1166 . 8785916 .
  26. Restructuring Living-Donor Liver Transplantation at a High-Volume Center During the COVID-19 Pandemic . 2021 . 33052181 . 2022-06-02 . Soin . A. S. . Choudhary . N. S. . Yadav . S. K. . Saigal . S. . Saraf . N. . Rastogi . A. . Bhangui . P. . Srinivasan . T. . Mohan . N. . Saha . S. K. . Gupta . A. . Chaudhary . R. J. . Yadav . K. . Dhampalwar . S. . Govil . D. . Gupta . N. . Vohra . V. . Journal of Clinical and Experimental Hepatology . 11 . 4 . 418–423 . 10.1016/j.jceh.2020.09.009 . 7543734 .
  27. Extrahepatic Malignancies and Liver Transplantation: Current Status . 2021 . 34276155 . Choudhary . N. S. . Saigal . S. . Saraf . N. . Soin . A. S. . Journal of Clinical and Experimental Hepatology . 11 . 4 . 494–500 . 10.1016/j.jceh.2020.10.008 . 8267344 .
  28. De Novo Malignancy After Living Donor Liver Transplantation: A Large Volume Experience . 2020 . 33029053 . Tiwari . A. . Saigal . S. . Choudhary . N. S. . Saha . S. . Rastogi . A. . Bhangui . P. . Saraf . N. . Srinivasan . T. . Yadav . S. K. . Gautam . D. . Nundy . S. . Soin . A. S. . Journal of Clinical and Experimental Hepatology . 10 . 5 . 448–452 . 10.1016/j.jceh.2020.02.001 . 7527845 .
  29. Experience With LDLT in Patients With Hepatocellular Carcinoma and Portal Vein Tumor Thrombosis Postdownstaging . 2020 . 32032291 . 2022-06-02 . Soin . A. S. . Bhangui . P. . Kataria . T. . Baijal . S. S. . Piplani . T. . Gautam . D. . Choudhary . N. S. . Thiagarajan . S. . Rastogi . A. . Saraf . N. . Saigal . S. . Transplantation . 104 . 11 . 2334–2345 . 10.1097/TP.0000000000003162 . 211064901 .
  30. Outcome of hepatitis C-related liver transplantation in direct-acting antiviral era . 2020 . 33230754 . 2022-06-02 . Choudhary . N. S. . Saraf . N. . Saigal . S. . Rastogi . A. . Bhangui . P. . Thiagrajan . S. . Soin . A. S. . Indian Journal of Gastroenterology . 39 . 6 . 539–543 . 10.1007/s12664-020-01105-z . 227133960 .
  31. Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis . 2021 . 34228774 . WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group . Shankar-Hari . M. . Vale . C. L. . Godolphin . P. J. . Fisher . D. . Higgins JPT . Spiga . F. . Savovic . J. . Tierney . J. . Baron . G. . Benbenishty . J. S. . Berry . L. R. . Broman . N. . Cavalcanti . A. B. . Colman . R. . De Buyser . S. L. . Derde LPG . Domingo . P. . Omar . S. F. . Fernandez-Cruz . A. . Feuth . T. . Garcia . F. . Garcia-Vicuna . R. . Gonzalez-Alvaro . I. . Gordon . A. C. . Haynes . R. . Hermine . O. . Horby . P. W. . Horick . N. K. . Kumar . K. . JAMA . 326 . 6 . 499–518 . 10.1001/jama.2021.11330 . 8261689 . 1854/LU-8716283 . 1 .
  32. Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific association for the study of the liver (APASL): an update . 2019 . 31172417 . Sarin . S. K. . Choudhury . A. . Sharma . M. K. . Maiwall . R. . Al Mahtab . M. . Rahman . S. . Saigal . S. . Saraf . N. . Soin . A. S. . Devarbhavi . H. . Kim . D. J. . Dhiman . R. K. . Duseja . A. . Taneja . S. . Eapen . C. E. . Goel . A. . Ning . Q. . Chen . T. . Ma . K. . Duan . Z. . Yu . C. . Treeprasertsuk . S. . Hamid . S. S. . Butt . A. S. . Jafri . W. . Shukla . A. . Saraswat . V. . Tan . S. S. . Sood . A. . Midha . V. . Hepatology International . 13 . 4 . 353–390 . 10.1007/s12072-019-09946-3 . 6728300 . 1 .
  33. Liver Transplantation for Hepatocellular Carcinoma. Working Group Report from the ILTS Transplant Oncology Consensus Conference . 2019 . 31172417 . Sarin . S. K. . Choudhury . A. . Sharma . M. K. . Maiwall . R. . Al Mahtab . M. . Rahman . S. . Saigal . S. . Saraf . N. . Soin . A. S. . Devarbhavi . H. . Kim . D. J. . Dhiman . R. K. . Duseja . A. . Taneja . S. . Eapen . C. E. . Goel . A. . Ning . Q. . Chen . T. . Ma . K. . Duan . Z. . Yu . C. . Treeprasertsuk . S. . Hamid . S. S. . Butt . A. S. . Jafri . W. . Shukla . A. . Saraswat . V. . Tan . S. S. . Sood . A. . Midha . V. . Hepatology International . 13 . 4 . 353–390 . 10.1007/s12072-019-09946-3 . 6728300 . 1 .
  34. Tocilizumab plus standard care versus standard care in patients in India with moderate to severe COVID-19-associated cytokine release syndrome (COVINTOC): an open-label, multicentre, randomised, controlled, phase 3 trial . 2019 . 31172417 . Sarin . S. K. . Choudhury . A. . Sharma . M. K. . Maiwall . R. . Al Mahtab . M. . Rahman . S. . Saigal . S. . Saraf . N. . Soin . A. S. . Devarbhavi . H. . Kim . D. J. . Dhiman . R. K. . Duseja . A. . Taneja . S. . Eapen . C. E. . Goel . A. . Ning . Q. . Chen . T. . Ma . K. . Duan . Z. . Yu . C. . Treeprasertsuk . S. . Hamid . S. S. . Butt . A. S. . Jafri . W. . Shukla . A. . Saraswat . V. . Tan . S. S. . Sood . A. . Midha . V. . Hepatology International . 13 . 4 . 353–390 . 10.1007/s12072-019-09946-3 . 6728300 . 1 .
  35. Recanalized umbilical vein as a conduit for anterior sector venous outflow reconstruction in right lobe grafts . 2021-05-29.
  36. Does the presence of jaundice and/or a lump in a patient with gall bladder cancer mean that the lesion is not resectable? . 2009 . 19657192 . 2021-05-29 . Varma . V. . Gupta . S. . Soin . A. S. . Nundy . S. . Digestive Surgery . 26 . 4 . 306–311 . 10.1159/000231880 . 22345979 .

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