Arnault Tzanck Explained

Arnault Tzanck
Birth Date:May 1, 1886
Birth Place:Vladikavkaz
Death Place:North Ossetia–Alania, Russia
Nationality:French
Field:medicine
Known For:blood transfusion

Arnault Tzanck (May 1, 1886 – February 18, 1954) was a French physician and a pioneer of blood transfusion. During the First World War, he was a doctor in the military ambulance where he realized the vital role of the blood transfusions.[1]

Arnault Tzanck's name is attached to an apparatus he invented that was widely used for transfusing blood in France between the wars, as well as a simple test he devised[2] using the microscopic analysis of scrapings from skin cancer lesions, different ganglia, and some forms of dermatitis especially pemphigus. The Tzanck smear is still widely used as a test for herpes, among other diseases.[3] A deep learning model was developed to analyze Tzanck smears and named after him as TzanckNet.[4] He also experimented with different methods of preserving blood and blood substitutes. Tzanck's most lasting contribution was in the organization of blood transfusion in France that eventually resulted in the creation of the Centre National de Transfusion Sanguine (National Blood Transfusion Center), which was established in 1949 with Tzanck as its first director. In the process, Tzanck educated a whole generation of serologists and immunologists, including Jean Dausset, Marcel Bessis, and Jean Pierre Soulier.

References

  1. Schneider. William H. April 2010. Arnault Tzanck, MD (1886-1954). Transfus Med Rev. 24. 2. 147–50. United States. 20303038. 10.1016/j.tmrv.2009.11.006.
  2. Tzanck. A.. 1947. Immediate cyto-diagnosis in dermatology. Annales de Dermatologie et de Syphiligraphie. 7. 2. 68. 0003-3979. 20253311.
  3. Book: Durdu, Murat. Cutaneous Cytology and Tzanck Smear Test. 2019. Springer International Publishing. 978-3-030-10721-5. en.
  4. Noyan. Mehmet Alican. Durdu. Murat. Eskiocak. Ali Haydar. 2020-10-27. TzanckNet: a convolutional neural network to identify cells in the cytology of erosive-vesiculobullous diseases. Scientific Reports. en. 10. 1. 18314. 10.1038/s41598-020-75546-z. 33110197. 7591506. 2045-2322. free.

See also