| State: | AR |
| Type: | AR |
| Route: | 354 |
| Maint: | AHTD |
| Map: | Arkansas 354.png |
| Length Mi1: | 9.70 |
| Length Ref1: | [1] |
| Direction A1: | West |
| Terminus A1: | , Oxford |
| Direction B1: | East |
| Terminus B1: | , Horseshoe Bend |
| Length Mi2: | 12.65 |
| Length Ref2: | [2] |
| Direction A2: | West |
| Terminus A2: | , Ash Flat |
| Direction B2: | East |
| Counties: | Izard, Sharp |
| Previous Type: | AR |
| Previous Route: | 353 |
| Next Type: | AR |
| Next Route: | 355 |
Arkansas Highway 354 is a designation for two east–west state highways in north Arkansas. The western segment of 9.7miles runs from Highway 9 in Oxford to Horseshoe Bend. An eastern segment of 12.65miles runs east from U.S. Route 167 in Ash Flat to Arkansas Highway 58.[3]
The route begins at AR 9 in Oxford. The route runs east to Horseshoe Bend, where it terminates at AR 289. This segment of highway is named Cardinal Road, and passes through the unincorporated community of Wiseman.[4]
Highway 354 begins in Ash Flat at US 167, and runs east as Main Street. The route winds southeast through Center to meet Arkansas Highway 58, where it terminates. Highway 354 runs along the southern part of the Harold E. Alexander Wildlife Management Area.
|-| colspan=6 align=center| Highway 354 eastern segment begins in Ash Flat|-