| State: | AR |
| Type: | AR |
| Route: | 259 |
| Map Custom: | yes |
| Map Notes: | AR 259 highlighted in red |
| Length Mi1: | 12.11 |
| Length Ref1: | [1] |
| Direction A1: | South |
| Direction B1: | North |
| Terminus B1: | at Lake Grove |
| Length Mi2: | 6.90 |
| Direction A2: | South |
| Direction B2: | North |
| Length Mi3: | 3.14 |
| Direction A3: | South |
| Direction B3: | North |
| Terminus B3: | near Hickory Ridge |
| Counties: | Lee, St. Francis, Cross |
| Previous Type: | AR |
| Previous Route: | 258 |
| Next Type: | AR |
| Next Route: | 260 |
Highway 259 (AR 259, Ark. 259, and Hwy. 259) is a designation for three north–south state highways in northeast Arkansas. A southern route of 12.11miles runs north from Highway 238 to US Route 70 (US 70) at Lake Grove, Arkansas.[2] A second route of 6.9miles begins at Highway 306 and runs north to Highway 284 in Cross County.[3] A third route of 3.14miles begins at Highway 364 and runs north to Highway 42 near Hickory Ridge.
Highway 259 begins at Highway 238 west of Moro and runs north past a cemetery before turning east and meeting Highway 78 at South Plains. The two routes have a brief concurrency north before Highway 78 splits to the northwest and Highway 259 continues north. Shortly after this junction, Highway 259 serves as the southern terminus for Highway 261. The highway runs north through New Salem before entering St. Francis County, where it terminates at US 70.
Highway 259 begins in the northwest corner of St. Francis County at Highway 306 and runs due north through flat farmland. The route runs into Cross County where it terminates at Highway 284. The highway does not cross or overlap with any other state highways and essentially serves as a connector route between two rural routes.
Highway 259 begins at Highway 364 in eastern Cross County. The route runs north through farmland to Highway 42 in Hickory Ridge, where it terminates.
Mile markers reset at concurrences.