Arkhypenko (Ukrainian: Архипенко), also transliterated as Arkhipenko, Archipenko, is a Ukrainian-language family name of patronymic derivation from the Slavic first name Arkhyp/Arkhip (Ukrainian: Архип) derived from the Greek name Archippus The Belarusian-language version is Arkhipienka.
The surname may refer to: