| Bridge Name: | Appleford Railway Bridge |
| Crosses: | River Thames |
| Locale: | Oxfordshire |
| Maint: | Network Rail |
| Design: | Bow and string |
| Material: | Iron |
| Height: | 13feet[1] |
| Open: | 1844 |
| Coordinates: | 51.6439°N -1.2404°W |
Appleford Railway Bridge carries the Cherwell Valley Line from Didcot to Oxford across the River Thames near the village of Appleford-on-Thames, Oxfordshire, England. It crosses the Thames on the reach between Clifton Lock and Culham Lock.
Originally, a timber bridge was built at the approximate location of the present bridge; by December 1843, it was reportedly under construction, and was completed during the following year.[2] By the 1850s, it has been replaced by a more substantial bridge principally composed of wrought iron so that heavier trains could be run along the line. A third bridge was completed in 1927, which was built out of steel; it is this structure that is presently used as of the 2010s.