| Appignano del Tronto | |
| Official Name: | Comune di Appignano del Tronto |
| Coordinates: | 42.9°N 53°W |
| Region: | Marche |
| Province: | Ascoli Piceno (AP) |
| Mayor: | Sara Moreschini |
| Area Total Km2: | 23.19 |
| Population Footnotes: | [1] |
| Population Total: | 1788 |
| Population As Of: | 30 April 2017 |
| Population Demonym: | Appignanesi |
| Elevation M: | 194 |
| Postal Code: | 63042 |
| Area Code: | 0736 |
Appignano del Tronto is a comune (municipality) in the Province of Ascoli Piceno in the Italian region Marche, located about 80km (50miles) south of Ancona and about 9km (06miles) northeast of Ascoli Piceno.
Appignano del Tronto borders the following municipalities: Ascoli Piceno, Castel di Lama, Castignano, Offida.