| Image Coa: | DEU Appenweier COA.svg |
| Coordinates: | 48.5397°N 7.98°W |
| Image Plan: | Appenweier in OG.svg |
| State: | Baden-Württemberg |
| Region: | Freiburg |
| District: | Ortenaukreis |
| Elevation: | 152 |
| Area: | 38.03 |
| Postal Code: | 77767 |
| Area Code: | 07805 |
| Licence: | OG, BH, KEL, LR, WOL |
| Gemeindeschlüssel: | 08 3 17 005 |
| Website: | www.appenweier.de |
| Mayor: | Viktor Lorenz[1] |
| Leader Term: | 2024 - 32 |
Appenweier (Swiss German; Alemannic; Alsatian: label=[[Low Alemannic German|Low Alemannic]]|Appewiir) is a municipality in western Baden-Württemberg, Germany in the district of Ortenau.
Appenweier consists of the main municipal Appenweier (4,075 inhabitants), Urloffen (4,301 inhabitants), known for horseradish-growing, and Nesselried (1,383 inhabitants). The Nesselried district runs through the Wannenbach valley, while Urloffen lies north of Appenweier.