The Apostolic Vicariate of the Comoros Archipelago is a Latin apostolic vicariate (missionary pre-diocesan jurisdiction) of the Roman Catholic Church in the Indian Ocean between insular Madagascar and continental Africa, comprising the Comoros and Mayotte, with a church in each.
The see is at Moroni, Comoros on Grande Comore island. It is exempt, i.e. directly subject to the Holy See, not part of any ecclesiastical province.
On 5 June 1975, the Holy See established an Apostolic Administration of Comoros on the present territory, which was split from the Diocese of Ambanja (on Madagascar), whose former last apostolic vicar and then first bishop was appointed to the new missionary post. On 1 May 2010, it was promoted as Apostolic Vicariate of the Comoros.
To date, all incumbents have been missionary members of three Latin congregations: