| Jurisdiction: | Apostolic Vicariate |
| Paksé | |
| Latin: | Vicariatus Apostolicus Paksensis |
| Local: | ອັກຄະສາວົກແທຂອງເມືອງປາກເຊ |
| Country: | Laos |
| Territory: | Champasak, Attapeu, Salavan/Saravan, and Sekong/Xekong |
| Episcopal Conference: | Episcopal Conference of Laos and Cambodia |
| Metropolitan: | Immediately subject to the Holy See |
| Coordinates: | 15.1173°N 105.8013°W |
| Area Km2: | 59,210 |
| Population: | 1,484,186 |
| Population As Of: | 2020 |
| Catholics: | 21,445[1] |
| Catholics Percent: | 1.44 |
| Parishes: | 57 |
| First Incumbent: | Jean-Pierre Urkia, M.E.P. |
| Denomination: | Roman Catholic |
| Sui Iuris Church: | Latin Church |
| Rite: | Roman Rite |
| Established: | 12 June 1967 |
| Cathedral: | Cathedral of the Sacred Heart in Pakse |
| Priests: | 8 |
| Bishop: | Andrew Souksavath Nouane Asa |
| Bishop Title: | Apostolic Vicar |
| Emeritus Bishops: | Cardinal Louis-Marie Ling Mangkhanekhoun, I.V.D. |
The Apostolic Vicariate of Pakse (Latin: Vicariatus Apostolicus Paksensis) is a Latin rite missionary territorial jurisdiction of the Catholic Church in Laos. As an apostolic vicariate, it is a pre-diocesan jurisdiction, entitled to a titular bishop. It covers southern Laos.
It is exempt, i.e., not part of any ecclesiastical province but directly dependent on the Holy See and notably its missionary Dicastery for Evangelization.
Its cathedral episcopal see is Cathedral of the Sacred Heart, in Pakse.
The vicariate was established on 12 June 1967 as Apostolic Vicariate of Pakse / Paksé (French) / 巴色 (正體中文) / Paksen(sis) (Latin adjective), when it was split off from the Apostolic Vicariate of Savannakhet.
The vicariate covers the Laotian provinces of Champasak, Salavan, Xekong and Attapu, but most of the Catholics live in Champasak and Saravan.
Covering an area of 45,000 km² of southern Laos, the Vicariate is the smallest of the apostolic vicariates in Laos. As of 2016, only about 15,000 (1.3%) of approximately 1.3 million people living in the area are members of the Catholic Church, half of them belonging to ethnic minorities. It is subdivided into 46 parishes served by only 7 priests. There are also 19 sisters from the Soeurs de la Charite (Sisters of Charity) and the Filles Marie de la Croix (Daughters of Mary of the Cross). As per 2014 it has 7 priests (6 diocesan, 1 religious), 22 lay religious (10 brothers, 12 sisters) and 16 seminarians.