APOF explained

Symbol:	APOF
Apolipoprotein F
Pfam:	PF15148
Interpro:	IPR026114

Apolipoprotein F is a protein that in humans is encoded for by the APOF gene.^{[1] [2]} The product of this gene is one of the minor apolipoproteins found in plasma. This protein forms complexes with lipoproteins and may be involved in transport and/or esterification of cholesterol.

Further reading

• Morton RE, Gnizak HM, Greene DJ . Lipid transfer inhibitor protein (apolipoprotein F) concentration in normolipidemic and hyperlipidemic subjects . J. Lipid Res. . 49 . 1 . 127–35 . 2008 . 17901467 . 10.1194/jlr.M700258-JLR200 . etal. free .
• Gerhard DS, Wagner L, Feingold EA . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Kabbara A, Payet N, Cottel D . Exclusion of CYP46 and APOM as candidate genes for Alzheimer's disease in a French population . Neurosci. Lett. . 363 . 2 . 139–43 . 2004 . 15172102 . 10.1016/j.neulet.2004.03.066 . 27752858 . etal.
• Anderson NL, Polanski M, Pieper R . The human plasma proteome: a nonredundant list developed by combination of four separate sources . Mol. Cell. Proteomics . 3 . 4 . 311–26 . 2004 . 14718574 . 10.1074/mcp.M300127-MCP200 . etal. free .
• Paromov VM, Morton RE . Lipid transfer inhibitor protein defines the participation of high density lipoprotein subfractions in lipid transfer reactions mediated by cholesterol ester transfer protein (CETP) . J. Biol. Chem. . 278 . 42 . 40859–66 . 2003 . 12907677 . 10.1074/jbc.M306580200 . free .
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Wang X, Driscoll DM, Morton RE . Molecular cloning and expression of lipid transfer inhibitor protein reveals its identity with apolipoprotein F . J. Biol. Chem. . 274 . 3 . 1814–20 . 1999 . 9880564 . 10.1074/jbc.274.3.1814 . free .
• Koren E, McConathy WJ, Alaupovic P . Isolation and characterization of simple and complex lipoproteins containing apolipoprotein F from human plasma . Biochemistry . 21 . 21 . 5347–51 . 1983 . 6816269 . 10.1021/bi00264a035 .
• Olofsson SO, McConathy WJ, Alaupovic P . Isolation and partial characterization of a new acidic apolipoprotein (apolipoprotein F) from high density lipoproteins of human plasma . Biochemistry . 17 . 6 . 1032–6 . 1978 . 204339 . 10.1021/bi00599a014 .

Notes and References

1. Day JR, Albers JJ, Gilbert TL, Whitmore TE, McConathy WJ, Wolfbauer G . Purification and molecular cloning of human apolipoprotein F . Biochem Biophys Res Commun . 203 . 2 . 1146–51 . Oct 1994 . 8093033 . 10.1006/bbrc.1994.2302 .
2. Web site: Entrez Gene: APOF apolipoprotein F.