| Apalachicola Historic District | |
| Nrhp Type: | hd |
| Nocat: | yes |
| Coordinates: | 29.7283°N -84.9919°W |
| Built: | 1836 |
| Architecture: | Mid 19th Century Revival, Late 19th And 20th Century Revivals, Late Victorian |
| Added: | November 21, 1980 |
| Refnum: | 80000951 |
The Apalachicola Historic District is a U.S. historic district in Apalachicola, Florida. It is bounded by the Apalachicola River, Apalachicola Bay, 17th and Jefferson Streets, encompasses approximately 4600 acres (19 km), and contains 652 historic buildings. On November 21, 1980, it was added to the U.S. National Register of Historic Places.