Aoife McLysaght explained

Aoife McLysaght
Workplaces:Trinity College Dublin
University of California, Irvine
Alma Mater:Trinity College Dublin (BA, PhD)
Thesis Title:Evolution of vertebrate genome organisation
Thesis Url:http://wolfe.ucd.ie/lab/pdfs/Aoife_McLysaght_PhD.pdf
Thesis Year:2002
Doctoral Advisor:Kenneth H. Wolfe
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Aoife McLysaght is an Irish geneticist and a professor in the Molecular Evolution Laboratory of the Smurfit Institute of Genetics, Trinity College Dublin in Ireland.

Education

McLysaght was educated at the Trinity College Dublin where she was awarded a Bachelor of Arts degree in Genetics in 1998, followed by a PhD in 2002 for research supervised by Kenneth H. Wolfe on the evolution of vertebrate genome organisation.[1] [2] [3] [4]

Career and research

Following her PhD, she completed postdoctoral research at the University of California, Irvine[5] working with Brandon Gaut before returning to work in Dublin in 2003. Her research in molecular evolution and comparative genomics has been published in leading peer-reviewed scientific journals including Nature,[6] Nature Genetics,[7] Bioinformatics,[8] Genome Research,[9] PNAS[10] [11] and the journal Yeast.[12]

She has served as senior editor and associate editor for the journals Molecular Biology and Evolution and Genome Biology and Evolution, and is on the editorial board of the journal Cell Reports. She is a member of the Society for Molecular Biology and Evolution (SMBE) and The Genetics Society. She served as Treasurer of SMBE 2012–14 and was elected President of the Society in 2017.[13]

Outreach and media

McLysaght is a regular contributor to public events, and has spoken at IGNITE Electric Picnic,[14] [15] TEDx, The Royal Institution, and on the BBC Radio 4 programme The Infinite Monkey Cage.[16] She brought genetics to a wider audience in the Royal Institution 2013 advent calendar[5] where she featured in videos on human chromosome 1,[17] human chromosome 14,[18] mitochondrial DNA (mtDNA)[19] and the Science Gallery, Dublin. In 2018 she joined with Alice Roberts to write and present the televised Royal Institution Christmas Lectures.[20]

Awards and honours

McLysaght was awarded European Research Council (ERC) Consolidator Grant 2018–23 and an ERC Starting Researcher grant from 2013 to 2018, and the President of Ireland Young Researcher's Award by Science Foundation Ireland (SFI) in 2005.[21] [22] She gave the J. B. S. Haldane lecture of The Genetics Society in 2016.[23] She was one of eight women scientists whose portrait was commissioned as part of the Royal Irish Academy's Women on Walls project.[24]

In 2010 she was elected a fellow of Trinity College Dublin.[25]

Personal life

McLysaght is a granddaughter of genealogist Edward MacLysaght.[26] McLysaght has two children, and a dog whose genome has been sequenced.[27]

Notes and References

  1. PhD. Trinity College Dublin. Evolution of vertebrate genome organisation. Aoife . McLysaght. 2002. 842498402. https://web.archive.org/web/20171106081749/http://wolfe.ucd.ie/lab/pdfs/Aoife_McLysaght_PhD.pdf. 2017-11-06.
  2. Aoife McLysaght's
  3. Web site: https://web.archive.org/web/20170711122103/http://wolfe.ucd.ie/lab/yore.php. 2017-07-11. Wolfe lab alumni. wolfe.ucd.ie. Ken. Wolfe. 2017.
  4. Web site: Aoife McLysaght Academic Tree. academictree.org.
  5. Web site: Professor brings science to life with flair. siliconrepublic.com. 2014. Claire. O’Connell.
  6. Lander. Eric S.. Eric Lander. Linton. Lauren M.. Birren. Bruce. Nusbaum. Chad. Zody. Michael C.. Baldwin. Jennifer. Devon. Keri. Dewar. Ken. Doyle. Michael. FitzHugh. William. Funke. Roel. Gage. Diane. Harris. Katrina. Heaford. Andrew. Howland. John. Kann. Lisa. Lehoczky. Jessica. LeVine. Rosie. McEwan. Paul. McKernan. Kevin. Meldrim. James. Mesirov. Jill P.. Miranda. Cher. Morris. William. Naylor. Jerome. Raymond. Christina. Rosetti. Mark. Santos. Ralph. Sheridan. Andrew. Sougnez. Carrie. Stange-Thomann. Nicole. Stojanovic. Nikola. Subramanian. Aravind. Wyman. Dudley. Rogers. Jane. Sulston. John. Ainscough. Rachael. Beck. Stephan. Bentley. David. Burton. John. Clee. Christopher. Carter. Nigel. Coulson. Alan. Deadman. Rebecca. Deloukas. Panos. Dunham. Andrew. Dunham. Ian. Durbin. Richard. French. Lisa. Grafham. Darren. Gregory. Simon. Hubbard. Tim. Humphray. Sean. Hunt. Adrienne. Jones. Matthew. Lloyd. Christine. McMurray. Amanda. Matthews. Lucy. Mercer. Simon. Milne. Sarah. Mullikin. James C.. Mungall. Andrew. Plumb. Robert. Ross. Mark. Shownkeen. Ratna. Sims. Sarah. Waterston. Robert H.. Wilson. Richard K.. Hillier. LaDeana W.. McPherson. John D.. Marra. Marco A.. Mardis. Elaine R.. Fulton. Lucinda A.. Chinwalla. Asif T.. Pepin. Kymberlie H.. Gish. Warren R.. Chissoe. Stephanie L.. Wendl. Michael C.. Delehaunty. Kim D.. Miner. Tracie L.. Delehaunty. Andrew. Kramer. Jason B.. Cook. Lisa L.. Fulton. Robert S.. Johnson. Douglas L.. Minx. Patrick J.. Clifton. Sandra W.. Hawkins. Trevor. Branscomb. Elbert. Predki. Paul. Richardson. Paul. Wenning. Sarah. Slezak. Tom. Doggett. Norman. Cheng. Jan-Fang. Olsen. Anne. Lucas. Susan. Elkin. Christopher. Uberbacher. Edward. Frazier. Marvin. Gibbs. Richard A.. Muzny. Donna M.. Scherer. Steven E.. Bouck. John B.. Sodergren. Erica J.. Worley. Kim C.. Rives. Catherine M.. Gorrell. James H.. Metzker. Michael L.. Naylor. Susan L.. Kucherlapati. Raju S.. Nelson. David L.. Weinstock. George M.. Sakaki. Yoshiyuki. Fujiyama. Asao. Hattori. Masahira. Yada. Tetsushi. Toyoda. Atsushi. Itoh. Takehiko. Kawagoe. Chiharu. Watanabe. Hidemi. Totoki. Yasushi. Taylor. Todd. Weissenbach. Jean. Heilig. Roland. Saurin. William. Artiguenave. Francois. Brottier. Philippe. Bruls. Thomas. Pelletier. Eric. Robert. Catherine. Wincker. Patrick. Rosenthal. André. Platzer. Matthias. Nyakatura. Gerald. Taudien. Stefan. Rump. Andreas. Smith. Douglas R.. Doucette-Stamm. Lynn. Rubenfield. Marc. Weinstock. Keith. Lee. Hong Mei. Dubois. JoAnn. Yang. Huanming. Yu. Jun. Wang. Jian. Huang. Guyang. Gu. Jun. Hood. Leroy. Rowen. Lee. Madan. Anup. Qin. Shizen. Davis. Ronald W.. Federspiel. Nancy A.. Abola. A. Pia. Proctor. Michael J.. Roe. Bruce A.. Chen. Feng. Pan. Huaqin. Ramser. Juliane. Lehrach. Hans. Reinhardt. Richard. McCombie. W. Richard. de la Bastide. Melissa. Dedhia. Neilay. Blöcker. Helmut. Hornischer. Klaus. Nordsiek. Gabriele. Agarwala. Richa. Aravind. L.. Bailey. Jeffrey A.. Bateman. Alex. Batzoglou. Serafim. Birney. Ewan. Bork. Peer. Brown. Daniel G.. Burge. Christopher B.. Cerutti. Lorenzo. Chen. Hsiu-Chuan. Church. Deanna. Clamp. Michele. Copley. Richard R.. Doerks. Tobias. Eddy. Sean R.. Eichler. Evan E.. Furey. Terrence S.. Galagan. James. Gilbert. James G. R.. Harmon. Cyrus. Hayashizaki. Yoshihide. Haussler. David. Hermjakob. Henning. Hokamp. Karsten. Jang. Wonhee. Johnson. L. Steven. Jones. Thomas A.. Kasif. Simon. Kaspryzk. Arek. Kennedy. Scot. Kent. W. James. Kitts. Paul. Koonin. Eugene V.. Korf. Ian. Kulp. David. Lancet. Doron. Lowe. Todd M.. McLysaght. Aoife. Mikkelsen. Tarjei. Moran. John V.. Mulder. Nicola. Pollara. Victor J.. Ponting. Chris P.. Schuler. Greg. Schultz. Jörg. Slater. Guy. Smit. Arian F. A.. Stupka. Elia. Szustakowki. Joseph. Thierry-Mieg. Danielle. Thierry-Mieg. Jean. Wagner. Lukas. Wallis. John. Wheeler. Raymond. Williams. Alan. Wolf. Yuri I.. Wolfe. Kenneth H.. Yang. Shiaw-Pyng. Yeh. Ru-Fang. Collins. Francis. Guyer. Mark S.. Peterson. Jane. Felsenfeld. Adam. Wetterstrand. Kris A.. Myers. Richard M.. Schmutz. Jeremy. Dickson. Mark. Grimwood. Jane. Cox. David R.. Olson. Maynard V.. Kaul. Rajinder. Raymond. Christopher. Shimizu. Nobuyoshi. Kawasaki. Kazuhiko. Minoshima. Shinsei. Evans. Glen A.. Athanasiou. Maria. Schultz. Roger. Patrinos. Aristides. Morgan. Michael J.. 11. Initial sequencing and analysis of the human genome. Nature. 409. 6822. 2001. 860–921. 0028-0836. 10.1038/35057062. 11237011. 2027.42/62798. free. free.
  7. McLysaght. Aoife. Hokamp. Karsten. Wolfe. Kenneth H.. Extensive genomic duplication during early chordate evolution. Nature Genetics. 31. 2. 2002. 200–204. 1061-4036. 10.1038/ng884. 12032567. 8263376.
  8. Pollastri. G.. McLysaght. A.. Porter: a new, accurate server for protein secondary structure prediction. Bioinformatics. 21. 8. 2004. 1719–1720. 1367-4803. 10.1093/bioinformatics/bti203. 15585524. free.
  9. Knowles. D. G.. McLysaght. A.. Recent de novo origin of human protein-coding genes. Genome Research. 19. 10. 2009. 1752–1759. 1088-9051. 10.1101/gr.095026.109. 2765279. 19726446.
  10. McLysaght. A.. Baldi. P. F.. Gaut. B. S.. Extensive gene gain associated with adaptive evolution of poxviruses. Proceedings of the National Academy of Sciences. 100. 26. 2003. 15655–15660. 0027-8424. 10.1073/pnas.2136653100. 14660798. 307623 . free.
  11. Makino. T.. McLysaght. A.. Ohnologs in the human genome are dosage balanced and frequently associated with disease. Proceedings of the National Academy of Sciences. 107. 20. 2010. 9270–9274. 0027-8424. 10.1073/pnas.0914697107. 20439718 . 2889102. free.
  12. McLysaght. Aoife. Enright. Anton J.. Skrabanek. Lucy. Wolfe. Kenneth H.. Estimation of Synteny Conservation and Genome Compaction Between Pufferfish (Fugu) and Human. Yeast. 1. 1. 2000. 22–36. 0749-503X. 10.1002/(SICI)1097-0061(200004)17:1<22::AID-YEA5>3.0.CO;2-S. 10797599. 2447035 .
  13. Web site: SMBE Council . smbe.org . Society for Molecular Biology & Evolution . 2019 . 21 January 2019.
  14. Web site: Aoife McLysaght at IGNITE Dublin #1. youtube.com. YouTube.
  15. Web site: Aoife McLysaght at IGNITE at Electric Picnic. youtube.com. YouTube.
  16. Web site: Alfred Russel Wallace: The Infinite Monkey Cage, Series 8 Episode 5 of 6. bbc.co.uk. BBC.
  17. Web site: Chromosome 1 – The Stuff of Life. youtube.com. YouTube.
  18. Web site: Chromosome 14 – Immunoglobulins: building our immune system. youtube.com. YouTube.
  19. Web site: Chromosome 24 – mtDNA, Lynn Margulis and the mitochondrial DNA. youtube.com. YouTube.
  20. Web site: CHRISTMAS LECTURES 2018: Who am I?. rigb.org. Royal Institution. 27 December 2018. 23 October 2019. https://web.archive.org/web/20191023210336/https://www.rigb.org/christmas-lectures/2018-who-am-i. dead.
  21. Web site: Professor Aoife Mclysaght. accenture.com. Accenture.
  22. Web site: Trinity Research: Professor Aoife McLysaght. tcd.ie.
  23. Web site: JBS Haldane Lecture – Genetics Society. genetics.org.uk.
  24. Web site: Women on Walls. www.ria.ie. Royal Irish Academy. 2020-12-26. 2016.
  25. Web site: Trinity Monday 2010 - Fellows and Scholars . www.tcd.ie . Trinity College Dublin . 12 April 2010 . 1 July 2023.
  26. Web site: The genetic imprint of Niall of the Nine Hostages. 2014. The Irish Times. irishtimes.com. Aoife. McLysaght.
  27. Web site: Cara Genome Project (@CaraGenome) | Twitter. twitter.com.

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