| Official Name: | Antsohimbondrona |
| Other Name: | Port Saint-Louis |
| Pushpin Map: | Madagascar |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location in Madagascar |
| Pushpin Mapsize: | 180 |
| Subdivision Type: | Country |
| Subdivision Name: | Madagascar |
| Subdivision Type1: | Region |
| Subdivision Name1: | Diana |
| Subdivision Type2: | District |
| Subdivision Name2: | Ambilobe |
| Population As Of: | 2001 |
| Population Total: | 32080 |
| Population Blank1 Title: | Ethnicities |
| Population Blank2 Title: | Religions |
| Timezone: | EAT |
| Utc Offset: | 3 |
| Coordinates: | -13.0833°N 99°W |
| Elevation Footnotes: | [1] |
| Elevation M: | 9 |
| Postal Code Type: | Postal code |
| Postal Code: | 204 |
Antsohimbondrona (also called: Port Saint-Louis) is a municipality in Madagascar. It belongs to the district of Ambilobe, which is a part of Diana Region. It is situated in the delta of the Mahavavy River into the Indian Ocean. According to 2001 census the population of Antsohimbondrona was 32080.
Antsohimbondrona has a maritime harbour. Primary and junior level secondary education are available in town. The town provides access to hospital services to its citizens. It is also a site of industrial-scale mining.
The majority (65%) of the population are farmers. The most important crop is sugarcane, while other important products are cotton and rice. Industry and services provide employment for 13% and 7% of the population, respectively. Additionally fishing employs 15% of the population.[2]
The provincial road 20D leads to Antsohimbondrona from Ambilobe.