| Antonio Ruberti | |
| Office: | Vice-President of the European Commission |
| Term Start: | 5 January 1993 |
| Term End: | 23 January 1995 |
| President: | Jacques Delors |
| Alongside: | Martin Bangemann, Leon Brittan, Henning Christophersen, Manuel Marín and Karel Van Miert |
| Office1: | European Commissioner for Science, Research, Technological Development, Education, Training and Youth |
| Term Start1: | 5 January 1993 |
| Term End1: | 23 January 1995 |
| President1: | Jacques Delors |
| Predecessor1: | Filippo Maria Pandolfi |
| Successor1: | Édith Cresson |
| Office2: | Minister of University and Scientific Research of Italy |
| Term Start2: | 29 July 1987 |
| Term End2: | 28 June 1992 |
| Primeminister2: | |
| Predecessor2: | Luigi Granelli |
| Successor2: | Alessandro Fontana |
| Birth Date: | 24 January 1927 |
| Birth Place: | Aversa, Italy |
| Death Place: | Rome, Italy |
| Party: | Italian Socialist Party |
Antonio Ruberti (24 January 1927 - 4 September 2000) was an Italian politician and engineer. He was a member of the Italian Government and a European Commissioner as well as a professor of engineering at La Sapienza University.
Antonio Ruberti was born in Aversa in the province of Caserta, Campania.
He trained as an engineer and taught control engineering and systems theory as the first head of the Department of Science and Engineering of La Sapienza university in Rome, a university of which he was later Rector.
In 1987, he joined the Italian government as Minister for the Coordination of Scientific and Technological Research. He held this position for five years. In 1992 Ruberti was elected to the Chamber of Deputies among the ranks of the Italian Socialist Party, where he sat until 1993, when he was appointed by the Italian government to the European Commission chaired by Delors with the portfolio covering science, research, technological development and education. Ruberti was only a commissioner until 1995 but during this short mandate, he launched a series of new initiatives including the Socrates and Leonardo da Vinci programmes, the European Week of Scientific Culture, and the European Science and Technology Forum. After leaving the commission, Ruberti was once more elected to the Chamber of Deputies, where he chaired the Committee for European Union Policies.
He died in Rome in 2000.