| Antonie Ruset | |
| Succession: | Prince of Moldavia |
| Reign1: | 10 November 1675 – November 1678 |
| Predecessor1: | Dumitrașcu Cantacuzino |
| Successor1: | George Ducas |
| House: | Ruset |
| Birth Date: | c. 1615 |
| Death Date: | 1685 |
| Religion: | Orthodox |
Antonie Ruset or Antonie Rosetti (c. 1615 – 1685) ruled from November 10, 1675 to November 1678 in the Principality of Moldova.
He came from an ancient family of Greek origin. Ruset ordered on March 29, 1677, the relocation of the seat of the Moldovan Metropolitan of the Romanian Orthodox Church from the former princely seat in Suceava in the current capital Iaşi, since according to Byzantine custom both the administrative and the ecclesiastical center of the empire in the same city had to be.