Anti-smooth muscle antibody explained

Anti-smooth muscle antibodies are antibodies (immunoglobulins) formed against smooth muscle. These antibodies are typically associated with autoimmune hepatitis.^{[1] [2]}

These antibodies can be directed against actin, troponin, and tropomyosin.^[3]

Notes and References

1. Dawkins . RL . Joske RA . Immunoglobulin deposition in liver of patients with active chronic hepatitis and antibody against smooth muscle . British Medical Journal . 2 . 5867 . 643–645 . June 1973 . 4577016 . 10.1136/bmj.2.5867.643 . 1589647 .
2. Book: M. Eric Gershwin. Liver immunology: principles and practice. 26 October 2010. 2007. Humana Press. 978-1-58829-818-8. 265–.
3. Book: Kenneth Michael Pollard. Autoantibodies and autoimmunity: molecular mechanisms in health and disease. 26 October 2010. 2006. Wiley-VCH. 978-3-527-31141-5. 293–.